Senior Scientist: Bioanalytical Method Development

Bristol-Myers Squibb Company; Princeton (NJ); On-site; USD 117,000 - 142,000; Full time

Benefits offered by this job

Wellbeing support

Retirement benefits

Insurance options

Company holidays

Job summary

Bristol Myers Squibb in Princeton, NJ, is seeking a Senior Scientist, Method Development (Regulated Bioanalysis) to lead and implement bioanalytical methods in development programs using LC-MS technologies. The role emphasizes leadership on method development, validation, and cross-functional study support across small and large molecules.

You will act as a technical expert on sample cleanup, chromatography, and mass spectrometry, interact with CROs, and mentor junior scientists while

Qualifications

• Ph.D. or equivalent advanced degree in the Life Sciences.
• 2+ of academic and/or industry experience.
• 4+ of academic and/or industry experience.
• Degree in chemistry, biochemistry, biology or related fields, plus relevant drug development experience at either a pharmaceutical company or a bioanalytical & biomarker CRO.
• Good understanding of bioanalysis & biomarker and their roles in drug development, including method development, validation, study support, and impact of quality bioanalytical/biomarker data to PK/PD correlation.
• Strong LC-MS/MS skills with separation and quantitation (or identification) of small or large molecule therapeutics and biomarkers in biological matrices.
• Experiences in performing LC-MS/MS and LBA method development, qualification/validation, and study sample analysis in a regulated environment to support preclinical and clinical studies.
• A proven track record of method development accomplishments in the field (thru presentations or publications).
• Good communication skills and experience in authoring and reviewing bioanalytical & biomarker assay, troubleshooting assay issues and direct junior scientist.
• Ability to multi-task and work in a collaborative team environment.
• Ability to communicate effectively in a team-based environment.

Responsibilities

• Evaluate and apply novel techniques or approaches to address challenging bioanalytical and biomarker issues.
• Conduct in-house bioanalytical and biomarker support for development programs with tandem mass spectrometry-based method development, validation, sample analysis, data interpretation, to report preparation in a regulated laboratory.
• Be the technical expert on sample cleanup, chromatography, mass spectrometric instrumentation, stability, and other method related issues.
• Interact with bioanalytical CROs to address method related issues and provide leadership for the knowledge transfer of novel technologies.
• Keep management apprised of project status and current scientific trends using written and oral summaries, as well as presentations.

Skills

LC-MS/MS expertise

Biomarker analysis

Regulated bioanalysis

Team leadership

Data interpretation

Education

Ph.D. in Life Sciences

Tools

Mass spectrometry

Chromatography

Instrumentation

Job description

Bristol Myers Squibb in Princeton, NJ, is seeking a Senior Scientist, Method Development (Regulated Bioanalysis) to lead and implement bioanalytical methods in development programs using LC-MS technologies. The role emphasizes leadership on method development, validation, and cross-functional study support across small and large molecules.

You will act as a technical expert on sample cleanup, chromatography, and mass spectrometry, interact with CROs, and mentor junior scientists while