Senior LNP Analytical Scientist — Assays & Method Dev

VetJobs; Cambridge (MA); Sur place; USD 87 000 - 105 000; Plein temps

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Stock options

Incentive pay

Résumé du poste

Bristol Myers Squibb in Cambridge, MA, is seeking a laboratory professional to perform analytical assays and support process development, stability, and quality control. The role emphasizes ELISA, HPLC, RNA-related techniques, and data interpretation within a GLP framework.

The candidate will work on multi-disciplinary teams, maintain critical equipment, prepare reagents, and ensure strict adherence to safety and regulatory guidelines. On-site role with competitive compensation.

Qualifications

• Bachelor's degree in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or related scientific discipline.
• 1–5 years of hands-on laboratory experience, preferably with RNA and/or LNPs including academic research, internships, or industry roles.
• Proficiency with ELISA, Western blotting, cell-based assays, UV-Vis spectroscopy, or qPCR.
• Proficiency with HPLC operations, including method execution, column management, and chromatography data system use (e.g., Empower, OpenLabs, Chromeleon). Experience or familiarity with mass spectrometry is a plus.
• Familiarity with RNA characterization techniques (e.g., SEC, CE, RT-PCR, RNAseq).
• Demonstrated ability to manage multiple priorities in a fast-paced environment while maintaining accuracy and attention to detail.
• Demonstrated ability to analyze data and present results to the team and the larger research community.
• Familiarity with ICH guidelines, GLP/GMP principles, and regulatory submission requirements.
• Experience with LIMS and Benchling is a plus.
• Experience with bioanalytical method validation (e.g., per FDA or EMA guidelines).
• Working knowledge of statistical analysis tools (e.g., GraphPad Prism, JMP, or Excel-based analysis).
• We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Responsabilités

• Perform routine analytical assays including ELISA, HPLC, and other analytical methods in support of research, process development, stability, and quality control activities
• Execute and document laboratory experiments according to established SOPs, protocols, and Good Laboratory Practice (GLP) standards
• Analyze, interpret, and summarize experimental data with accuracy; prepare clear and concise lab reports and technical summaries
• Maintain laboratory equipment including calibration, troubleshooting, and coordination with vendors for preventive maintenance
• Prepare reagents, buffers, and standards required for analytical testing; manage inventory of laboratory consumables and supplies
• Support method development and optimization efforts under the guidance of senior scientists
• Ensure compliance with all safety regulations, environmental health and safety (EHS) guidelines, and BMS corporate policies
• Contribute to cross-functional teams, collaborating with colleagues in research, process development, and formulations

Connaissances

ELISA

Western blotting

Cell-based assays

qPCR

RNA characterization

Data analysis

Statistical analysis tools

Formation

Associates

Bachelor's degree in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or related scientific discipline

Outils

HPLC

Chromatography data systems

Empower

OpenLabs

Chromeleon

LIMS

Benchling

GraphPad Prism

JMP

Excel

Description du poste

Bristol Myers Squibb in Cambridge, MA, is seeking a laboratory professional to perform analytical assays and support process development, stability, and quality control. The role emphasizes ELISA, HPLC, RNA-related techniques, and data interpretation within a GLP framework.

The candidate will work on multi-disciplinary teams, maintain critical equipment, prepare reagents, and ensure strict adherence to safety and regulatory guidelines. On-site role with competitive compensation.