Senior RNA Process Development & Manufacturing Scientist

Addition Therapeutics; South San Francisco (CA); On-site; USD 76,000 - 96,000; Full time

Job summary

Addition Therapeutics in South San Francisco, CA is seeking a Scientist at the Research Associate/Senior Research Associate level to contribute to RNA production and scalable manufacturing processes. The role emphasizes cross-functional collaboration and meticulous documentation.

You will produce RNA in small to mid-scale reactions, prepare reagents, support vendor qualification, and help develop protocols while staying current with literature to improve quality and efficiency.

Qualifications

• Bachelor's or master's degree in chemistry or biochemistry with 2–4 years of experience.
• Experience manufacturing DNA, RNA or gene therapy modalities (GMP or non-GMP).
• Strong documentation practice with electronic notebooks.
• Thrives in a fast-moving, results-oriented startup environment.
• Experience with external vendor communications.

Responsibilities

• Produce RNA in small to mid-scale reactions.
• Prepare reagents, sub-aliquot, maintain logs and inventory.
• Support reagent selection and vendor qualification.
• Contribute to creating and documenting protocols and techniques.
• Collaborate with the analytical team to determine purity and levels of undesired impurities in DNA and RNA products.
• Support QC assays.
• Collect and prepare accurate and timely data summaries and review written reports.
• Stay current with relevant scientific literature and implement new techniques or practices to improve quality and efficiency.

Skills

Attention to detail

Cross-functional collaboration

Electronic notebooks

Education

Bachelor's degree in Chemistry or Biochemistry

Master's degree preferred

Tools

Qubit

Fragment Analyzer

LAL Endotoxin

Job description

Addition Therapeutics in South San Francisco, CA is seeking a Scientist at the Research Associate/Senior Research Associate level to contribute to RNA production and scalable manufacturing processes. The role emphasizes cross-functional collaboration and meticulous documentation.

You will produce RNA in small to mid-scale reactions, prepare reagents, support vendor qualification, and help develop protocols while staying current with literature to improve quality and efficiency.