QC Research Associate, RNA Therapeutics & Cell Assays

Addition Therapeutics; San Francisco (CA); On-site; USD 114,616,000 - 143,270,000; Full time

Benefits offered by this job

Competitive salary

Equity

Benefits

SSF location

Job summary

Addition Therapeutics in South San Francisco is seeking a Research Associate to join the Quality Control team. The role focuses on in vitro potency and characterization testing, maintaining cell lines and reference standards, and analyzing dose–response data to release RNA-based materials.

You will work with Process Development and Formulation teams, perform aseptic QC assays (cell-based potency, luciferase, ELISA), and help develop robust QC methods as our platform moves toward the clinic.

Qualifications

• BS in Biology, Biochemistry, Molecular/Cell Biology, Bioengineering or related life-science discipline.
• 4–5 years of relevant lab experience (BS) or 1–2 years (MS) are required.
• Hands-on mammalian cell culture and aseptic technique essential.
• Experience with cell-based potency assays or plate-based biochemical assays (ELISA).
• Proficiency in dose–response data analysis and curve fitting.

Responsibilities

• Perform routine in vitro QC release and characterization assays (cell-based potency/functional assays, ELISAs).
• Prepare reference standards, standard curves, and serial dilutions; determine relative potency.
• Apply acceptance criteria and system-suitability metrics for data integrity.
• Maintain mammalian cell lines; monitor growth and viability.
• Document lab records and contribute to SOPs and validation reports.
• Support cross-functional Process Development and Formulation teams.

Skills

Cell culture

Aseptic technique

Potency assays

ELISA

Data analysis

GraphPad Prism

SoftMax Pro

Education

BS in Biology or related life-science

MS in related field

Tools

GraphPad Prism

SoftMax Pro

Job description

Addition Therapeutics in South San Francisco is seeking a Research Associate to join the Quality Control team. The role focuses on in vitro potency and characterization testing, maintaining cell lines and reference standards, and analyzing dose–response data to release RNA-based materials.

You will work with Process Development and Formulation teams, perform aseptic QC assays (cell-based potency, luciferase, ELISA), and help develop robust QC methods as our platform moves toward the clinic.