Onsite RNA Process Scientist – Scale-Up & Tech Transfer

Meet Life Sciences; Boston (MA); On-site; USD 80,000 - 110,000; Full time

Job summary

Meet Life Sciences in Boston is seeking a Senior Research Associate to support the Process Sciences team, developing and scaling xRNA production from lab through intermediate scale. The role centers on in vitro transcription, downstream purification, process optimization, and analytical characterization of RNA products in a collaborative lab/office setting.

You will work with Process Sciences leadership on internal programs and client-facing development, perform IVT reactions, troubleshoot

Qualifications

• Bachelor’s degree in Pharmaceutical Sciences, Engineering, or related with 1–2 years of relevant experience, or Master’s with hands-on RNA/xRNA or drug substance process development.
• Hands-on experience with IVT and xRNA/mRNA production processes including scale-up or tech transfer.
• Experience with AKTA chromatography and purification, TFF and downstream process development.
• Experience using analytical characterization techniques: Fragment Analyzer, CE, Bioanalyzer/gel, UV, NanoDrop.
• Strong written and verbal communication, with good lab safety practices and GMP-like environments.

Responsibilities

• Perform and support IVT reactions at small and intermediate scales.
• Troubleshoot and optimize IVT and downstream purification processes.
• Execute chromatography and purification activities for IVT products (AKTA, TFF).
• Conduct analytical characterization of RNA products (purity, concentration).
• Maintain rigorous documentation and support technology transfer and manufacturing activities.

Skills

Hands-on RNA process development

Analytical characterization

Written and verbal communication

Lab safety and GMP awareness

Team collaboration

Education

Bachelor's in Pharmaceutical Sciences/Engineering or related (1-2 years)

Master’s with RNA/xRNA or drug substance process development experience

Tools

AKTA chromatography

Tangential Flow Filtration (TFF)

Fragment Analyzer

Capillary electrophoresis

Bioanalyzer

UV spectroscopy

NanoDrop

Job description

Meet Life Sciences in Boston is seeking a Senior Research Associate to support the Process Sciences team, developing and scaling xRNA production from lab through intermediate scale. The role centers on in vitro transcription, downstream purification, process optimization, and analytical characterization of RNA products in a collaborative lab/office setting.

You will work with Process Sciences leadership on internal programs and client-facing development, perform IVT reactions, troubleshoot