Senior Project Manager - CNS (North America)

Worldwide Clinical Trials; Charlotte (NC); Remote; USD 120,000 - 180,000; Full time

Job summary

Worldwide Clinical Trials in the United States is seeking a Senior Project Manager CNS to lead Phase I–IV clinical trials with global reach. You will own study delivery from start-up through closeout, ensuring timelines, quality, and budgets are met while building strong client relationships.

You will lead cross-functional teams, manage resources and financial performance, and drive process improvements across global projects, with travel as required.

Qualifications

• 7+ years in clinical pharma project management or equivalent CRO leadership.
• Experience leading cross-functional, CNS clinical research teams.
• Strong financial, budgeting, and contract management skills.
• Solid knowledge of ICH/GCP and global regulatory standards.
• Excellent communication and stakeholder management.
• Willingness to travel domestically and internationally.

Responsibilities

• Lead cross-functional project teams from start-up to closeout across Phase I–IV.
• Drive planning, execution, tracking, and risk management to meet timelines and budgets.
• Coordinate internal and external partners and vendors for seamless execution.
• Serve as primary client contact and maintain strong relationships.
• Manage resources and develop contingency plans to sustain momentum.
• Monitor financial performance and support revenue targets.
• Promote collaboration and resolve issues across global teams.
• Ensure deliverables meet contract, client, and SOP requirements.
• Drive process improvements to raise efficiency and quality.

Skills

Project management

CRO/pharma experience

Budget management

Cross-functional leadership

ICH/GCP knowledge

Stakeholder management

Fluent English

Project management software

Tools

Project management software

Job description

It is built by those who take pioneering, creative approaches and implement them with quality and excellence.

We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs – in the best possible way.

Why Worldwide

Make an Impact as a Senior Project Manager at Worldwide

As a Senior Project Manager CNS, you will play a critical role in delivering Phase I-IV clinical trials that have local, regional, or global reach. You will take ownership of study delivery from start-up through closeout, ensuring projects are executed efficiently while meeting quality, timeline, and budget expectations.

In this highly visible role, you will serve as a key point of contact for clients, leading cross-functional teams and driving collaboration across internal stakeholders, external partners, and vendors. You will combine strategic thinking, operational oversight, and financial management to guide projects to success while fostering strong client relationships and supporting a culture of excellence, accountability, and continuous improvement.

This is a remote role open to candidates based in Central or Eastern Europe. Travel will be required on an as-needed basis, including domestic and international travel as required by project needs.

• Lead cross-functional project teams to deliver Phase I-IV clinical trials from start-up through closeout.
• Drive project planning, execution, tracking, and risk management to ensure successful delivery against timeline, quality, and budget objectives.
• Coordinate internal teams, external partners, and subcontractors to ensure seamless project execution.
• Serve as the primary client contact, building trusted relationships and ensuring high levels of client satisfaction.
• Manage project resources, identify potential gaps, and develop contingency plans to maintain project momentum.
• Monitor project financial performance and contribute to meeting assigned revenue and budget targets.
• Facilitate collaboration, resolve conflicts, and promote effective teamwork across global project teams.
• Ensure project deliverables meet contractual requirements, client expectations, and applicable clinical research standards and SOPs.
• Drive process improvements that enhance operational efficiency and quality across assigned projects.

• Minimum 7 years of clinical pharmaceutical industry experience, including demonstrated clinical project management experience; alternatively, significant healthcare supervisory experience combined with clinical research experience in the pharmaceutical or CRO industry.
• Proven experience leading multidisciplinary, cross-functional project teams and managing CNS clinical research projects is required for this role.
• Strong understanding of project management principles, including scope, timelines, quality, resources, and cost management.
• Solid financial acumen, including experience developing and managing project budgets.
• Thorough knowledge of ICH Guidelines, Good Clinical Practice (GCP), and international regulatory requirements governing clinical development programs.
• Experience using project management software and strong organizational, communication, negotiation, and stakeholder management skills.
• Fluent in English, both written and verbal, and fluent in the local office language; valid passport and driver's license required, with willingness to travel domestically and internationally as needed.

At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.

The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):

The final salary will be determined based on relevant experience, performance, education, and internal equity. We ensure pay equity and transparency and comply with all applicable labor laws.

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