Senior Project Manager - CNS (North America)

Worldwide Clinical Trials; North Carolina; Remote; USD 110,000 - 150,000; Full time

Job summary

Worldwide Clinical Trials is seeking a Senior Project Manager CNS to lead Phase I–IV clinical trials with global reach. You will own study delivery from start-up to closeout, guiding timelines, quality, and budgets while serving as the main client contact.

In this remote role, you will coordinate cross-functional teams and vendors, manage risk and finances, and drive continuous improvement, ensuring compliance with ICH, GCP, and regulatory standards across projects.

Qualifications

• Minimum 7 years of clinical pharmaceutical industry experience with clinical project management.
• Proven ability to lead multidisciplinary, cross-functional project teams in CNS clinical research.
• Strong understanding of PM principles: scope, timelines, quality, resources, cost management.
• Solid financial acumen including budgeting experience.
• Thorough knowledge of ICH, GCP, and regulatory standards governing clinical development.
• Experience using project management software and strong organizational, communication, and stakeholder skills.
• Fluent in English; willingness to travel domestically and internationally.

Responsibilities

• Lead cross-functional project teams to deliver Phase I-IV clinical trials from start-up through closeout.
• Drive project planning, execution, tracking, and risk management to meet timeline, quality, and budget objectives.
• Coordinate internal teams, external partners, and subcontractors for seamless project execution.
• Serve as the primary client contact, building trusted relationships and ensuring high client satisfaction.
• Manage project resources, identify gaps, and develop contingency plans to maintain momentum.
• Monitor project financial performance and contribute to meeting revenue and budget targets.
• Facilitate collaboration, resolve conflicts, and promote effective teamwork across global project teams.
• Ensure deliverables meet contractual requirements, client expectations, and applicable standards.
• Drive process improvements to enhance efficiency and quality across projects.

Skills

Cross-functional leadership

Budget management

Risk management

Stakeholder management

Negotiation

Project planning

Client relationship management

Financial management

Communication

Job description

It is built by those who take pioneering, creative approaches and implement them with quality and excellence.

We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs - in the best possible way.

Why Worldwide

Make an Impact as a Senior Project Manager at Worldwide

As a Senior Project Manager CNS, you will play a critical role in delivering Phase I-IV clinical trials that have local, regional, or global reach. You will take ownership of study delivery from start-up through closeout, ensuring projects are executed efficiently while meeting quality, timeline, and budget expectations.

In this highly visible role, you will serve as a key point of contact for clients, leading cross-functional teams and driving collaboration across internal stakeholders, external partners, and vendors. You will combine strategic thinking, operational oversight, and financial management to guide projects to success while fostering strong client relationships and supporting a culture of excellence, accountability, and continuous improvement.

This is a remote role open to candidates based in Central or Eastern Europe. Travel will be required on an as-needed basis, including domestic and international travel as required by project needs.

• Lead cross-functional project teams to deliver Phase I-IV clinical trials from start-up through closeout.
• Drive project planning, execution, tracking, and risk management to ensure successful delivery against timeline, quality, and budget objectives.
• Coordinate internal teams, external partners, and subcontractors to ensure seamless project execution.
• Serve as the primary client contact, building trusted relationships and ensuring high levels of client satisfaction.
• Manage project resources, identify potential gaps, and develop contingency plans to maintain project momentum.
• Monitor project financial performance and contribute to meeting assigned revenue and budget targets.
• Facilitate collaboration, resolve conflicts, and promote effective teamwork across global project teams.
• Ensure project deliverables meet contractual requirements, client expectations, and applicable clinical research standards and SOPs.
• Drive process improvements that enhance operational efficiency and quality across assigned projects.

Minimum 7 years of clinical pharmaceutical industry experience, including demonstrated clinical project management experience; alternatively, significant healthcare supervisory experience combined with clinical research experience in the pharmaceutical or CRO industry.

Proven experience leading multidisciplinary, cross-functional project teams and managing CNS clinical research projects is required for this role.

Strong understanding of project management principles, including scope, timelines, quality, resources, and cost management.

Solid financial acumen, including experience developing and managing project budgets.

Thorough knowledge of ICH Guidelines, Good Clinical Practice (GCP), and international regulatory requirements governing clinical development programs.

Experience using project management software and strong organizational, communication, negotiation, and stakeholder management skills.

Fluent in English, both written and verbal, and fluent in the local office language; valid passport and driver's license required, with willingness to travel domestically and internationally as needed.

At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.

The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):

The final salary will be determined based on relevant experience, performance, education, and internal equity. We ensure pay equity and transparency and comply with all applicable labor laws. To view our other roles, check out our careers page at Discover a world of difference at Worldwide ! For more information on Worldwide, visit or connect with us on LinkedIn.