Senior Program Director, Biotech Development & Portfolio

Torque Bio, Inc.; United States; On-site; USD 170,000 - 210,000; Full time

Job summary

Torque Bio is seeking an experienced Associate Director Program & Portfolio Management to oversee end-to-end development of pipeline candidates through IND submission and clinical development. This hands-on leader will build integrated plans, drive cross-functional decisions, and ensure alignment across scientific, regulatory, and clinical workstreams.

The role requires strategic planning, detailed execution, and effective communication with internal teams, external partners, and senior

Qualifications

• Bachelor’s degree in life sciences, engineering, business, or a related discipline required.
• Advanced degree such as MS, MBA, PhD, PharmD, or equivalent is preferred.
• PMP or equivalent certification is a bonus.
• 8+ years of relevant experience in biotechnology, pharmaceutical, biologics, gene therapy, or a related development environment, including substantial cross-functional program or project management responsibility.
• Demonstrated experience advancing development programs through IND-enabling activities, IND submission, and entry into clinical development.
• Developing and managing program-level budgets and forecasts in partnership with Finance and functional leaders.
• Operating in a development-stage or lean outsourced biotechnology organization is strongly preferred.
• Experience managing clinical trial programs, including integrated planning across clinical and supporting functions.
• Proficiency in managing patent applications and/or business agreements with legal counsel guidance.

Responsibilities

• Lead integrated program management for one or more pipeline candidates, spanning research transition, preclinical development, IND-enabling activities, CMC, regulatory submission, and clinical execution.
• Build and maintain integrated development plans, timelines, decision points, dependencies, resource assumptions, and critical paths that connect functional plans to corporate milestones.
• Lead cross-functional program team meetings, establish clear governance and operating procedures, document decisions, and ensure timely completion of actions.
• Partner with functional leaders to translate program strategy into executable workplans with clearly defined deliverables, owners, and completion criteria.
• Anticipate program risks, facilitate scenario planning, maintain risk and issue registers, and drive mitigation and escalation when milestones or decisions are at risk.
• Lead program financial planning by developing forecasts, managing budgets and variances, and integrating cost, timeline, scope, and resource considerations into program decisions.
• Flex into leadership of clinical project management as candidates transition into the clinic, ensuring continuity from development strategy through study start-up and execution.
• Keep the integrated clinical project plan in sync across Clinical Operations, Medical, Regulatory, CMC, Quality, Data Management, Biostatistics, Pharmacovigilance, and external service providers.
• Support clinical trial planning and execution, including study start-up, site activation planning, vendor deliverables, enrollment assumptions, clinical supply dependencies, data milestones, and closeout activities.

Skills

Development planning

Dependency management

Critical path analysis

Risk management

Governance

Executive reporting

Education

Bachelor's degree

Advanced degree preferred

PMP certification bonus

Job description

Torque Bio is seeking an experienced Associate Director Program & Portfolio Management to oversee end-to-end development of pipeline candidates through IND submission and clinical development. This hands-on leader will build integrated plans, drive cross-functional decisions, and ensure alignment across scientific, regulatory, and clinical workstreams.

The role requires strategic planning, detailed execution, and effective communication with internal teams, external partners, and senior