Senior Director, Oncology Program Lead

Generate:Biomedicines; Somerville (MA); On-site; USD 190,000 - 230,000; Full time

Job summary

Generate:Biomedicines seeks a Senior Director, Scientific Project Lead, Oncology to steer complex programs from concept through preclinical development, shaping translational strategy and guiding portfolio decisions.

The role combines people management with broad leadership across research, translational, and development functions, partnering with executives to align teams, mitigate risks, and drive high-quality data-driven decisions.

Qualifications

• PhD, MD, or MD/PhD in cancer biology, immuno-oncology, or related field.
• 12+ years of relevant experience in biotech, pharma, academia, or related scientific environment.
• Experience identifying, evaluating, or advancing therapeutic targets and preclinical programs in oncology.
• Experience designing or interpreting preclinical oncology studies and translating findings into hypotheses.
• Experience managing scientists and leading multidisciplinary teams through influence.
• Ability to synthesize complex scientific issues into sound decisions and governance recommendations.

Responsibilities

• Lead cross-functional scientific programs from concept through preclinical development with accountability for strategy, execution, and governance.
• Develop integrated program strategies aligning objectives, timelines, dependencies, and resourcing.
• Set program direction, advance opportunities, and integrate biology, platform capabilities, and evidence for decision-making.
• Facilitate discussions, resolve diverse viewpoints, and drive clear recommendations and go/no-go decisions.
• Drive execution across wet lab, computational, translational, and preclinical workstreams with high-quality data packages.
• Build resource plans and budget assumptions, anticipate inflection points, and resolve risks and dependencies.
• Establish operating mechanisms for governance, risk tracking, and cross-functional accountability.
• Manage, coach, and develop direct reports and mentor team members in partnership with managers.
• Foster a high-performing culture rooted in rigor, accountability, collaboration, and urgency.

Skills

Scientific leadership

Program management

Cross-functional collaboration

People management

Strategic decision making

Budget & resourcing

Education

PhD/MD/MD-PhD in cancer biology/immuno-oncology

Job description

Generate:Biomedicines seeks a Senior Director, Scientific Project Lead, Oncology to steer complex programs from concept through preclinical development, shaping translational strategy and guiding portfolio decisions.

The role combines people management with broad leadership across research, translational, and development functions, partnering with executives to align teams, mitigate risks, and drive high-quality data-driven decisions.