Senior Process Engineer

ZETA; King of Prussia (PA); Hybrid; USD 120,000 - 170,000; Full time

Benefits offered by this job

PTO

Coffee & Tea

Health benefits

401K match

Travel opportunities

Job summary

ZETA in King of Prussia is seeking a Senior Process Engineer to lead process design and engineering activities for biopharmaceutical client projects, including upstream, downstream, and GMP-compliant systems. You will collaborate across engineering teams to deliver high-quality solutions.

The role requires a Bachelor’s in engineering and at least 10 years in biotech/pharma, with knowledge of GMPs and biopharmaceutical process systems.

Qualifications

• Bachelor’s degree in Engineering or related technical discipline.
• Minimum 10 years of Biotech/Pharma experience.
• Knowledge of GMP requirements and biopharmaceutical process systems.

Responsibilities

• Deliver the process engineering scope on time and on budget, aligned with quality and compliance.
• Prepare and review PFDs, P&IDs, and mass/energy balances.
• Design process equipment such as vessels, mixing systems, and filtration skids.
• Develop URS and Functional Specifications.
• Lead start-up activities including FAT and SAT.
• Provide technical support to stakeholders.
• Coordinate with automation, mechanical, and project management teams.
• Develop CIP/SIP strategies and cycle design.

Education

Bachelor’s degree in Engineering or related technical discipline

Job description

About Us

ZETA is a global engineering and technology partner serving pharmaceutical and biopharma companies. With over 30 years of experience, we specialize in process engineering, automation, and GMP-compliant systems to help deliver life-saving therapies.

Position Summary

The Senior Process Engineer is responsible for leading process design and engineering activities for ZETA’s biopharmaceutical client projects. This role supports the development of process systems including upstream, downstream, blood plasma fractionation, ADCs, and cell and gene therapy applications. The Senior Process Engineer collaborates with cross-functional engineering teams to deliver high-quality, GMP-compliant solutions.

Location: King of Prussia
Contract: Full-time employee
Start: 27.10.2026

Duties and Responsibilities

• Accountable for delivering the process engineering scope on time, on budget, and in accordance with quality and compliance requirements.
• Prepare and review process engineering documentation, including PFDs, P&IDs, and mass/energy balances.
• Specify and design process equipment such as vessels, mixing systems, filtration skids, and related components.
• Develop User Requirements Specifications (URS) and Functional Specifications.
• Lead and execute start-up and commissioning activities including FAT and SAT.
• Provide process troubleshooting and technical support to internal and external stakeholders.
• Coordinate with automation, mechanical, and project management teams to ensure alignment across engineering disciplines.
• Develop CIP/SIP strategies, including cycle design, testing, and optimization.

Required Qualifications

• Bachelor’s degree in Engineering or related technical discipline.
• Minimum 10 years of experience in the Biotech/Pharmaceutical industry.
• Knowledge of GMP requirements and biopharmaceutical process systems.

Preferred Qualifications

• Experience with bioprocess unit operations such as buffer/media prep, upstream, or downstream processing.
• Prior experience supporting capital projects.

Work Environment & Physical Requirements

• Hybrid work model with three onsite days per week at the King of Prussia office.
• Travel up to 30%, including domestic and international assignments as needed for project execution, FAT/SAT, or client support.
• Ability to work in an office, client sites, and manufacturing environments as needed.

We offer

• European-style PTO & vacation
• Free coffee & Teas
• Medical, Dental, & Vision Health Benefits & HSA & Short-term Disability
• 401K with 5% employer match of annual salary
• Travel & training