Senior Process Engineer

ZETA GmbH

King of Prussia (PA)

Hybrid

USD 120,000 - 170,000

Full time

14 days+

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Benefits offered by this job

European-style PTO

Health benefits

401K with match

Travel & training

Free coffee/tea

Job summary

ZETA GmbH in King of Prussia is seeking a Senior Process Engineer to lead process design for biopharma client projects, supporting upstream, downstream, and cell therapy applications.

You will collaborate with cross-functional teams to deliver GMP-compliant solutions, develop URS/FS, PFDs and P&IDs, and lead start-up activities including FAT and SAT across facilities.

Qualifications

Bachelor’s degree in Engineering or related technical discipline.
Minimum 10 years of Biotech/Pharma experience.
Knowledge of GMP requirements and biopharmaceutical process systems.
Experience with bioprocess unit operations such as upstream/downstream processing.

Responsibilities

Lead process design and engineering activities for biopharma client projects.
Prepare and review PFDs, P&IDs, and mass/energy balances.
Design process equipment such as vessels and filtration skids.
Develop URS and Functional Specifications.
Lead start-up and commissioning activities including FAT and SAT.
Coordinate with automation, mechanical, and project management teams to align disciplines.

Skills

Process design

GMP knowledge

Biopharma experience

Cross-functional collaboration

Documentation (PFDs/P&IDs)

Education

Bachelor’s degree in Engineering

Job description

About Us

ZETA is a global engineering and technology partner serving pharmaceutical and biopharma companies. With over 30 years of experience, we specialize in process engineering, automation, and GMP-compliant systems to help deliver life-saving therapies.

Position Summary

The Senior Process Engineer is responsible for leading process design and engineering activities for ZETA’s biopharmaceutical client projects. This role supports the development of process systems including upstream, downstream, blood plasma fractionation, ADCs, and cell and gene therapy applications. The Senior Process Engineer collaborates with cross-functional engineering teams to deliver high-quality, GMP-compliant solutions.

Senior Process Engineer

Location: King of Prussia Contract: Full-time employee Start: 27.10.2026

Duties and Responsibilities

Accountable for delivering the process engineering scope on time, on budget, and in accordance with quality and compliance requirements.
Prepare and review process engineering documentation, including PFDs, P&IDs, and mass/energy balances.
Specify and design process equipment such as vessels, mixing systems, filtration skids, and related components.
Develop User Requirements Specifications (URS) and Functional Specifications.
Lead and execute start-up and commissioning activities including FAT and SAT.
Provide process troubleshooting and technical support to internal and external stakeholders.
Coordinate with automation, mechanical, and project management teams to ensure alignment across engineering disciplines.
Develop CIP/SIP strategies, including cycle design, testing, and optimization.

Required Qualifications

Bachelor’s degree in Engineering or related technical discipline.
Minimum 10 years of experience in the Biotech/Pharmaceutical industry.
Knowledge of GMP requirements and biopharmaceutical process systems.

Preferred Qualifications

Experience with bioprocess unit operations such as buffer/media prep, upstream, or downstream processing.
Prior experience supporting capital projects.

Work Environment & Physical Requirements

Hybrid work model with three onsite days per week at the King of Prussia office.
Travel up to 30%, including domestic and international assignments as needed for project execution, FAT/SAT, or client support.
Ability to work in an office, client sites, and manufacturing environments as needed.

We offer

European-style PTO & vacation