Senior Principal Statistical Programmer – Remote Leader

WCG Clinical, Inc.; San Juan (PR); Remote; USD 131,000 - 160,000; Full time

Benefits offered by this job

Health insurance

401(k) with company match

Tuition reimbursement

Training and certification support

Paid holidays

Sick time

Career development opportunities

Job summary

WCG is seeking a Senior Principal Statistical Programmer to lead statistical programming for complex clinical trials and DMC deliverables. This role blends hands-on SAS and R work with technical leadership to standardize outputs across studies, including datasets, tables, listings, and figures.

You will mentor staff, shape programming standards, and partner with biostatistics and data management to support regulatory submissions and CDISC compliance. Remote option with national scope.

Qualifications

• Minimum 8–10 years of statistical programming experience in a clinical trial environment.
• Deep expertise in SAS programming, including complex analyses and regulatory deliverables.
• Proficiency in R programming.
• Demonstrated experience with CDISC standards and regulatory requirements.
• Proven ability to independently lead complex programming efforts across studies.
• Experience mentoring staff and driving technical standards.
• Demonstrated ability to coordinate biostatistical projects with minimal direction.

Responsibilities

• Serve as a senior technical expert in statistical programming across multiple studies or functional areas.
• Design, develop, validate, and oversee complex statistical programming deliverables (datasets, tables, listings, and figures).
• Lead the development, validation, and continuous improvement of DMC macros and programming standards.
• Provide technical oversight to ensure quality, compliance, and consistency across deliverables.
• Drive the establishment and adoption of programming standards, best practices, and process improvements.
• Collaborate with biostatistics and study teams to support complex trial designs, analyses, and DMC reporting.
• Mentor and provide technical leadership to statistical programming staff.

Skills

SAS programming

R programming

CDISC standards

Regulatory deliverables

Mentoring staff

Project leadership

Education

Master’s degree

Tools

SAS macros

Job description

WCG is seeking a Senior Principal Statistical Programmer to lead statistical programming for complex clinical trials and DMC deliverables. This role blends hands-on SAS and R work with technical leadership to standardize outputs across studies, including datasets, tables, listings, and figures.

You will mentor staff, shape programming standards, and partner with biostatistics and data management to support regulatory submissions and CDISC compliance. Remote option with national scope.