Senior Principal Scientist, Polysaccharide Bioprocess Lead

Pfizer; Pearl River (NY); On-site; USD 124,000 - 207,000; Full time

Benefits offered by this job

401(k) with company match

Health benefits

Paid vacation

Job summary

Pfizer in the United States is seeking a Senior Principal Scientist to lead the Polysaccharide Fermentation and Purification Development group within Vaccines, EBPD. You will shape strategy and provide scientific leadership for upstream and downstream process development to support diverse vaccine portfolios.

The role emphasizes cross-functional collaboration, technology transfer, risk management, and mentoring of staff to deliver scalable, compliant manufacturing processes for clinical and

Qualifications

• PhD in Chemical Engineering or related field with 8+ years in vaccine process development.
• Hands-on depth in microbial fermentation and polysaccharide recovery/purification.
• Experience with quality-by-design, DOE, and regulatory expectations for clinical manufacturing.

Responsibilities

• Lead upstream and downstream process development teams to drive vaccines programs.
• Develop robust, scalable manufacturing processes transferable across facilities.
• Guide technology transfer to clinical manufacturing sites with risk assessments and controls.
• Mentor staff and foster innovation using digital tools and data-driven approaches.

Skills

Leadership

Cross-functional collaboration

Project management

Data analysis

Education

PhD in Chemical Engineering or related

Job description

Pfizer in the United States is seeking a Senior Principal Scientist to lead the Polysaccharide Fermentation and Purification Development group within Vaccines, EBPD. You will shape strategy and provide scientific leadership for upstream and downstream process development to support diverse vaccine portfolios.

The role emphasizes cross-functional collaboration, technology transfer, risk management, and mentoring of staff to deliver scalable, compliant manufacturing processes for clinical and