Senior Principal Scientist, Computational Safety & AI

Biopharma Careers; Ridgefield (CT); On-site; USD 140,000 - 269,000; Full time

Job summary

Boehringer Ingelheim is seeking a Senior Principal/Principal Scientist, Computational Safety, to lead in silico safety strategies across drug discovery and development in Ridgefield, CT. You will leverage AI/ML and multi-omics data to identify liabilities and inform risk-based decisions, collaborating with toxicology, bioinformatics, and IT teams.

Responsibilities include developing integrated safety packages, advancing foundation models for safety, and communicating actionable insights to

Qualifications

• PhD in Computational Toxicology, Computational Biology, Bioinformatics, Molecular Biology, or related field.
• Strong collaboration, scientific leadership, and communication skills with ability to translate complex results.

Responsibilities

• Lead and/or generate in silico target safety assessment strategy development.
• Develop and deliver integrated computational safety packages to support program and portfolio decisions.
• Advance AI/ML and multi omics-based models, including foundation models, for safety and liability prediction.
• Drive AI enabled Adverse Outcome Pathway development to support mechanistic risk assessment.
• Proactively identify and communicate on target and off target safety risks.
• Collaborate with Toxicology, Discovery, Clinical Safety, Bioinformatics, Data Science, and IT teams.
• Bridge communication of complex computational insights to multidisciplinary stakeholders.

Skills

Collaboration

Leadership

Communication

Education

PhD in Computational Toxicology

Job description

Boehringer Ingelheim is seeking a Senior Principal/Principal Scientist, Computational Safety, to lead in silico safety strategies across drug discovery and development in Ridgefield, CT. You will leverage AI/ML and multi-omics data to identify liabilities and inform risk-based decisions, collaborating with toxicology, bioinformatics, and IT teams.

Responsibilities include developing integrated safety packages, advancing foundation models for safety, and communicating actionable insights to