Senior Neurodegeneration Clinical Lead: Huntington's Program

Alnylam Pharmaceuticals; Cambridge (MA); Hybrid; USD 250,000 - 380,000; Full time

Job summary

Alnylam Pharmaceuticals in Cambridge, MA (hybrid with Maidenhead, UK) seeks Senior Director, Clinical Research – Neurodegeneration to lead clinical development programs, primarily Huntington’s disease, and guide proof-of-concept studies through regulatory interactions.

You will work across Regulatory, Biostatistics, Clinical Operations and Research, shape development strategies, oversee trials and deliverables, and present findings to internal and external stakeholders.

Qualifications

• MD with strong research background and publications.
• 10+ years industry or academic clinical experience.
• Experience leading Phase 2/3 Huntington’s drug development.

Responsibilities

• Provide strategic leadership for clinical programs.
• Lead development to secure global regulatory approvals.
• Oversee trial conduct and safety.
• Collaborate with Regulatory, Biostatistics, Medical and Research teams.
• Interact with external experts and health authorities.

Skills

MD/MD PhD

Leadership

Clinical development

Regulatory interactions

Education

MD or MD/PhD

Job description

Alnylam Pharmaceuticals in Cambridge, MA (hybrid with Maidenhead, UK) seeks Senior Director, Clinical Research – Neurodegeneration to lead clinical development programs, primarily Huntington’s disease, and guide proof-of-concept studies through regulatory interactions.

You will work across Regulatory, Biostatistics, Clinical Operations and Research, shape development strategies, oversee trials and deliverables, and present findings to internal and external stakeholders.