Senior Medical Director

Advanced Clinical; Warszawa; On-site; PLN 704,000 - 939,000; Full time

Benefits offered by this job

Health coverage

Life insurance

Disability insurance

401(k) benefits

Job summary

Advanced Group in Warsaw seeks a Senior Medical Director to lead clinical development for Huntington’s disease and an expanding RNAi portfolio, guiding programs from early development through regulatory approval.

You will oversee trial design, safety, timelines and deliverables while collaborating with Research, Preclinical, Regulatory Affairs, Medical Affairs, Biostatistics, and Clinical Operations to ensure integrated development plans.

Qualifications

• MD or PhD with strong research background and peer-reviewed publications.
• 10+ years of industry or equivalent clinical academic experience.
• Proven leadership of Phase 2/3 clinical programs and regulatory interactions.
• Strong expertise in clinical research, trial design, biostatistics, and regulatory requirements.

Responsibilities

• Provide strategic leadership and clinical oversight for neurodegeneration programs.
• Develop and execute clinical development strategies to support global regulatory approvals.
• Oversee trial conduct, safety, timelines and key deliverables across Clinical Research and Operations.
• Collaborate cross-functionally to ensure integrated development plans.
• Advise research teams on clinical feasibility and study design.
• Lead major written deliverables including regulatory submissions and publications.
• Review and approve key clinical documents in line with SOPs.
• Represent Development at regulatory interactions and external collaborations.

Skills

Leadership

Regulatory knowledge

Clinical trial design

Cross-functional collaboration

Communication

Education

MD or PhD with strong research background

Board certification or specialist training

Job description

Senior Medical Director

Code: 36255 Posted: 2026-05-08 Type: Contract Remote: No Salary Range: $0 Per Hour Category: Clinical Development

Overview

Our client is seeking an experienced physician drug developer to provide clinical leadership across a growing RNAi therapeutics portfolio. This role will primarily lead clinical development in Huntington’s disease while supporting additional therapeutic areas as pipeline assets evolve. The position drives clinical strategy, operational excellence, and cross-functional collaboration to advance programs from early development through regulatory approval.

Key Responsibilities

• Provide strategic leadership and clinical oversight for neurodegeneration clinical programs.
• Develop and execute innovative, practical clinical development strategies to support global regulatory approvals.
• Oversee trial conduct, safety, timelines, and key deliverables across Clinical Research and Operations.
• Collaborate cross-functionally with Research, Preclinical, Regulatory Affairs, Medical Affairs, Commercial, Biostatistics, and Clinical Operations to ensure integrated development plans.
• Advise research teams on clinical feasibility of novel targets and proof-of-concept study design.
• Lead major written deliverables, including regulatory submissions, publications, abstracts, and presentations.
• Review and approve key clinical documents (protocols, IBs, informed consent forms) in line with SOPs.
• Represent Development at regulatory interactions, scientific meetings, and external collaborations.

Experience and Qualifications

• MD or PhD with strong research background and peer-reviewed publications; board certification or specialist training preferred.
• 10+ years of industry or equivalent clinical academic experience.
• Proven leadership of Phase 2/3 clinical programs and regulatory interactions.
• Strong expertise in clinical research, trial design, biostatistics, and regulatory requirements.
• Excellent communication, leadership, and cross-functional collaboration skills.
• Experience in neurology (Huntington’s disease) and work with biotech/pharma partners is a plus.
• Thrives in a fast-paced, entrepreneurial biotech environment.

Full-time employees are also eligible for benefits options such as health coverage, life insurance, disability insurance, and 401k benefits.

At Advanced Group, our commitment to diversity and inclusion in every part of our organization is crucial to fulfilling our mission and demonstrating our REAL values. Advanced Group is committed to providing employment opportunities without regard to sex, race, color, age, national origin, religion, gender identity or expression, sexual orientation or sexual preference, pregnancy or maternity, genetic information, marital status, disability, veteran status, or any other basis protected by applicable federal, state or local law.

Advanced Group complies with federal and state disability laws and makes reasonable accommodations for applicants and candidates with disabilities. If a reasonable accommodation is needed to participate in the job application or interview process, please contact [email protected].