Senior Mechanical Design Engineer

ZETA GmbH; King of Prussia (PA); Hybrid; USD 110,000 - 170,000; Full time

Benefits offered by this job

Free Coffee

Medical, Dental, & Vision Health Benef

401K with 5% employer match of annual

Travel & Training

Hybrid Work Schedule

Job summary

ZETA GmbH in King of Prussia is seeking a Senior Mechanical Design Engineer to lead mechanical design activities for biopharma client projects, driving development of advanced process systems for upstream processing, downstream purification, and cell therapies.

You will mentor junior engineers, lead design reviews, ensure GMP and ASME BPE compliance, and collaborate across cross‑functional teams to deliver robust mechanical solutions.

Qualifications

• Bachelor’s degree in Mechanical Engineering or related field.
• 7+ years of mechanical design experience, preferably in biopharma or process industries.
• Proficiency in 2D and 3D CAD modeling, design standards and engineering best practices.
• Strong understanding of sanitary design, materials, welding, and fabrication methods.

Responsibilities

• Lead Mechanical Engineering scope throughout the full project lifecycle.
• Lead development of complex 3D models, assemblies, and mechanical system designs.
• Develop P&IDs, 2D layouts, specifications, detailed drawings, and engineering documentation.
• Ensure designs comply with GMP, ASME BPE, and relevant engineering standards.
• Oversee and mentor junior engineers, providing technical guidance.
• Translate process engineering requirements into robust mechanical solutions.
• Lead mechanical design reviews, DFMEAs, tolerance analyses, and risk assessments.
• Collaborate with fabrication, automation, and process engineering teams.
• Support clients, vendors, and manufacturing teams throughout the project lifecycle.

Skills

Mechanical design

CAD modeling

Mentoring & leadership

GMP/ASME knowledge

Education

Bachelor's degree in Mechanical Engineering

Job description

Senior Mechanical Design Engineer

Location: King of Prussia

Contract: Full-time employee

Start: 30.11.2026

Your tasks

The Senior Mechanical Design Engineer leads mechanical design and engineering activities for ZETA’s biopharmaceutical client projects. This role drives the design and development of advanced process systems for upstream processing, downstream purification, plasma fractionation, ADC manufacturing, and cell and gene therapy applications.

The Senior Mechanical Design Engineer serves as a technical leader, guiding junior engineers, leading design reviews, ensuring GMP and ASME BPE compliance, and acting as a key contributor in cross‑functional engineering teams.

Key Responsibilities

• Lead Mechanical Engineering scope throughout the full project lifecycle.
• Lead development of complex 3D models, assemblies, and mechanical system designs.
• Develop P&IDs, 2D layouts, specifications, detailed drawings, and engineering documentation.
• Ensure designs comply with GMP, ASME BPE, and relevant engineering standards.
• Oversee and mentor junior engineers, providing technical guidance.
• Translate process engineering requirements into robust mechanical solutions.
• Lead mechanical design reviews, DFMEAs, tolerance analyses, and risk assessments.
• Collaborate with fabrication, automation, and process engineering teams.
• Support clients, vendors, and manufacturing teams throughout the project lifecycle. including customer meetings and design reviews.

Your profile

• Bachelor’s degree in Mechanical Engineering or related field.
• 7+ years of mechanical design experience, preferably in biopharma or process industries.
• Proficiency in 2D and 3D CAD modeling, design standards, and engineering best practices.
• Strong understanding of sanitary design, materials, welding, and fabrication methods.
• Experience leading engineering projects and mentoring junior team members.
• Ability to work cross‑functionally and manage technical aspects of client projects.

Work Environment & Physical Requirements

• Hybrid work model with three onsite days per week at the King of Prussia office.
• Travel up to 15%, including domestic and international assignments as needed for project execution, FAT/SAT, or client support.

We offer

competitive PTO & Vacation and Hybrid Work Schedule

• Free Coffee
• Medical, Dental, & Vision Health Benefits
• competitive PTO & Vacation and Hybrid Work Schedule
• 401K with 5% employer match of annual salary
• Travel & Training

2200 Renaissance Blvd Ste. 170, King of Prussia, PA 19406