Senior Manufacturing Associate

Immatics-US; Houston (TX); On-site; USD 85,000 - 120,000; Full time

Benefits offered by this job

Health benefits

4 weeks vacation

Holidays (12)

Life insurance

Disability insurance

401(k) with match

Parental leave

Job summary

Immatics-US is seeking a Senior Manufacturing Associate to support the CMC-GMP Manufacturing team in a clinical manufacturing setting. You will lead complex cell processing, ensure GMP compliance, and provide technical guidance across manufacturing activities.

The role emphasizes documentation accuracy, batch execution, and continuous improvement, reporting to the Manufacturing Manager at the Stafford, TX site.

Qualifications

• Requires Associate’s or Bachelor’s degree in a scientific field (biology, biotechnology, etc.).
• 4+ years of GMP-regulated manufacturing experience, preferably in cell therapy or biologics.
• Experience executing aseptic processing in cleanrooms (Grade A–D).
• Strong documentation practices compliant with ALCOA++ and cGDocP.

Responsibilities

• Execute and verify cell processing activities (culture, enrichment, cryopreservation, thawing, washing).
• Lead manufacturing runs and mentor junior staff.
• Maintain compliant batch records and documentation per ALCOA++ and cGDocP.
• Identify deviations and support investigations, CAPAs, and quality systems.

Skills

GMP manufacturing

Aseptic processing

Documentation (ALCOA++)

CAPA investigations

Process improvement

Education

Associate’s or Bachelor’s degree in a scientific field

Tools

ALCOA++

cGDocP

IQ/OQ/PQ

GMP knowledge

Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.Why Join Us?Innovative Environment: Help to pioneer advancements in cancer immunotherapy.Collaborative Culture: Be part of a diverse team dedicated to your professional growth.Global Impact: Contribute to therapies that make a lasting impact on patients globally.Role OverviewWe are seeking a Senior Manufacturing Associate to support our CMC-GMP Manufacturing team. In this role, you will lead and execute complex, time-sensitive cell processing and testing activities for patient-derived cellular products in a clinical manufacturing environment. You will be responsible for ensuring compliance with GMP standards, maintaining product integrity and sterility, and overseeing accurate documentation and batch execution. As a senior team member, you will also provide technical guidance, support process improvements, and contribute to maintaining high operational standards across manufacturing activities.Schedule: 1430 – 2300; Monday to FridayReports to: Manufacturing ManagerLocation: 13203 Murphy Road Suite 100 Stafford, TX 77477Basic Qualifications:Associate’s or Bachelor’s degree in a scientific field (e.g., biology, biotechnology, or related discipline)4+ years of experience in GMP-regulated manufacturing, preferably in cell therapy or biologicsDemonstrated experience executing aseptic processing and working in cleanroom environments (Grade A–D)Proven ability to maintain compliant documentation in accordance with ALCOA++ and cGDocP standardsExperience identifying deviations and supporting investigations, CAPAs, and quality systemsPreferred Qualifications:Bachelor’s degree in a scientific fieldExperience in cell therapy manufacturing, including cell culture, cryopreservation, and cell processing techniquesFamiliarity with GLP, GTP, and industry standards (e.g., FACT, CAP, CLIA)Experience supporting validation activities (IQ/OQ/PQ) and change control processesAdvanced troubleshooting skills and ability to resolve complex manufacturing or equipment issuesExperience mentoring or training junior staff and contributing to team developmentDemonstrated ability to drive process improvements in a GMP-regulated environmentIn this role you will:Execute and verify cell processing activities, including cell culture, enrichment, cryopreservation, thawing, and washingPerform manufacturing operations in compliance with GMP, GLP, GTP, and applicable regulatory standardsMaintain accurate, compliant documentation and batch records in line with ALCOA++ and cGDocP requirementsEnsure aseptic handling and cleanroom compliance to maintain product sterility and integrityIdentify, document, and support investigation of deviations, including CAPA implementationPerform calculations, equipment maintenance, and routine manufacturing support activitiesLead manufacturing runs, mentor junior team members, and contribute to continuous improvement initiativesWhat do we offer?At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics:Comprehensive Benefits:Competitive rates for Health, Dental, and Vision Insurance4 weeks of vacation, granted up front each year and prorated for first and last year of employment.12 company paid holidays7 days of sick time100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars100% employer-paid short- and long-Term disability coverage401(k) with immediate eligibility and company match…The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.Partially paid parental leave for eligible employees.Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.Equal Employment OpportunityWe are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.Reasonable AccommodationsWe are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at [e-mail] AuthorizationApplicants must be authorized to work in the United States without the need for current or future sponsorship. Visa sponsorships may be available for certain roles.Pre-Employment RequirementsEmployment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.