Principal Manufacturing Associate

Immatics-US; Houston (TX); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Competitive health insurance

Generous vacation and holidays

401(k) with company match

Parental leave benefits

Job summary

Immatics, a leader in cancer immunotherapy, seeks a Principal Manufacturing Associate to oversee on-the-floor cell therapy operations in a cGMP setting. This role provides leadership, training, and deviation support while coordinating shift activities and ensuring regulatory compliance.

Responsibilities include batch record reviews, collaboration with MSAT/PD teams, and guiding staff through policies and procedures. On-site role in Stafford, TX with a strong emphasis on safety and efficiency.

Qualifications

• Experience working in a cGMP cell therapy environment.
• Experience leading or supervising manufacturing staff.
• Ability to interpret and review batch records and deviations.

Responsibilities

• Provide leadership and training to staff in alignment with cGMP requirements.
• Coordinate shift activities and ensure on-time execution of manufacturing tasks.
• Review batch records and document deviations; support investigations and resolutions.
• Collaborate with MSAT/PD teams to transfer projects into GMP.
• Lead routine team meetings and communicate across shifts and with managers.

Skills

cGMP knowledge

leadership

batch records review

training & coaching

communication

Education

Biomanufacturing AS degree or related

Biomanufacturing Level 2 Certificate

Associate degree in Biology/Biochemistry/Biotechnology

Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.Why Join Us?Innovative Environment: Help to pioneer advancements in cancer immunotherapy.Collaborative Culture: Be part of a diverse team dedicated to your professional growth.Global Impact: Contribute to therapies that make a lasting impact on patients globally.We are seeking a Principal Manufacturing Associate to support our CMC-GMP team. This individual will provide direct leadership and oversight for the on-the-floor operations of cell therapy manufacturing in a cGMP environment.Schedule: 7:00am - 3:30pm; Monday to Friday; On-siteReports to: Manufacturing ManagerLocation: 13203 Murphy Road Suite 100 Stafford, TX 77477Basic Qualifications:Biomanufacturing Technology Associate of Applied Science Degree, Biomanufacturing Technology Level 2 Certificate, or equivalent. or an Associate degree in Biology, Biochemistry, Biotechnology, Biomanufacturing or another related field.7+ years of cell therapy manufacturing experience, or 4+ years of cell therapy manufacturing experience combined with lead or supervisory experience.In this role you will:As a Principal Manufacturing Associate, you will play a key role in supporting our CMC-GMP operations:Knowledge and adherence to cGMP requirements.Provide leadership, guidance, and necessary training to staff in alignment with cGMP requirements and established proceduresProvide instruction to facilitate workflow, shift activities, and shift exchange ensuring all activities are completed as assigned.Provide a safe and controlled work environment.Provide deviation workflow support, including, but not limited to initiating, investigating, and troubleshooting deviations and unexpected events.Serve as backup for manufacturing associates for daily manufacturing processes.Review executed batch records and documents.Coordinate with the Training Department to include training needs on the manufacturing schedule.Clear communication with outgoing and incoming shift Leads and Managers to disseminate all relevant information.Collaborate with the MSAT/PD teams to transfer new projects into GMP.Develop or update internal policies, procedures or steps, identifies and escalate risks, communicates changes and plan for execution.Leads routine team meetings and huddles.Ability to work productively and to participate in a highly creative and fast-paced environment.Work Environment:cGMP clean room spaces and facilities (~80% of work hours).Grade A/B/C/D GMP environment with associated facility noise levels.While performing the duties of this job, you may routinely handle blood components and is occasionally exposed to temperatures between -196°C and 40°C, liquid nitrogen, liquid nitrogen vapor, dry ice, and carbon dioxide.Lifting: raising or lowering an object (up to 25 lbs.) from one level to another (includes upward pulling).Undergo and pass a color blindness evaluation and assessment of vision abilities required for this position.Must be able to push or pull carts and gas tanks on rolling wheels (approximately 50 lbs.).What do we offer?At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics:Comprehensive Benefits:Competitive rates for Health, Dental, and Vision Insurance4 weeks of vacation granted up front each year and prorated for first and last year of employment.12 company paid holidays7 days of sick time100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars100% employer-paid short- and long-Term disability coverage401(k) with immediate eligibility and company match…The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.Partially paid parental leave for eligible employees.Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.Equal Employment OpportunityWe are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.Reasonable AccommodationsWe are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at [e-mail] AuthorizationApplicants must be authorized to work in the United States without the need for current or future sponsorship. Visa sponsorships may be available for certain roles.Pre-Employment RequirementsEmployment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.