Senior Manufacturing Associate

Immatics; Houston (TX); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Health, Dental, Vision Insurance

Vacation: 4 weeks + 12 holidays

Life Insurance

Disability coverage

401(k) with company match

Parental leave

Job summary

Immatics is hiring a Senior Manufacturing Associate to support the CMC-GMP Manufacturing team in a clinical manufacturing environment. You will lead complex cell processing, ensure GMP compliance, maintain documentation, and provide technical guidance. The role includes mentoring junior staff and driving continuous improvements across manufacturing activities.

Location: 13203 Murphy Rd, Stafford, TX 77477. Schedule: 1430–2300, Monday–Friday. Reports to Manufacturing Manager.

Qualifications

• Associate's or Bachelor’s degree in a scientific field.
• 4+ years of experience in GMP-regulated manufacturing, preferably in cell therapy or biologics.
• Demonstrated experience executing aseptic processing and working in cleanroom environments (Grade A–D).
• Proven ability to maintain compliant documentation in accordance with ALCOA++ and cGDocP standards
• Experience identifying deviations and supporting investigations, CAPAs, and quality systems

Responsibilities

• Execute and verify cell processing activities, including cell culture, enrichment, cryopreservation, thawing, and washing.
• Perform manufacturing operations in compliance with GMP, GLP, GTP, and applicable regulatory standards
• Maintain accurate, compliant documentation and batch records in line with ALCOA++ and cGDocP requirements
• Ensure aseptic handling and cleanroom compliance to maintain product sterility and integrity
• Identify, document, and support investigation of deviations, including CAPA implementation
• Perform calculations, equipment maintenance, and routine manufacturing support activities
• Lead manufacturing runs, mentor junior team members, and contribute to continuous improvement initiatives

Skills

GMP manufacturing

Aseptic processing

Documentation

Cell therapy manufacturing

Quality systems

CAPA

Team mentoring

Education

Associate’s or Bachelor’s degree in a scientific field

Bachelor’s degree in a scientific field

Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview

We are seeking a Senior Manufacturing Associate to support our CMC-GMP Manufacturing team. In this role, you will lead and execute complex, time-sensitive cell processing and testing activities for patient-derived cellular products in a clinical manufacturing environment. You will be responsible for ensuring compliance with GMP standards, maintaining product integrity and sterility, and overseeing accurate documentation and batch execution. As a senior team member, you will also provide technical guidance, support process improvements, and contribute to maintaining high operational standards across manufacturing activities.

Schedule

1430 – 2300; Monday to Friday

Reports to

Manufacturing Manager

Location

13203 Murphy Road Suite 100 Stafford, TX 77477

Basic Qualifications

• Associate’s or Bachelor’s degree in a scientific field (e.g., biology, biotechnology, or related discipline)
• 4+ years of experience in GMP-regulated manufacturing, preferably in cell therapy or biologics
• Demonstrated experience executing aseptic processing and working in cleanroom environments (Grade A–D)
• Proven ability to maintain compliant documentation in accordance with ALCOA++ and cGDocP standards
• Experience identifying deviations and supporting investigations, CAPAs, and quality systems

Preferred Qualifications

• Bachelor’s degree in a scientific field
• Experience in cell therapy manufacturing, including cell culture, cryopreservation, and cell processing techniques
• Familiarity with GLP, GTP, and industry standards (e.g., FACT, CAP, CLIA)
• Experience supporting validation activities (IQ/OQ/PQ) and change control processes
• Advanced troubleshooting skills and ability to resolve complex manufacturing or equipment issues
• Experience mentoring or training junior staff and contributing to team development
• Demonstrated ability to drive process improvements in a GMP-regulated environment

In This Role You Will

• Execute and verify cell processing activities, including cell culture, enrichment, cryopreservation, thawing, and washing
• Perform manufacturing operations in compliance with GMP, GLP, GTP, and applicable regulatory standards
• Maintain accurate, compliant documentation and batch records in line with ALCOA++ and cGDocP requirements
• Ensure aseptic handling and cleanroom compliance to maintain product sterility and integrity
• Identify, document, and support investigation of deviations, including CAPA implementation
• Perform calculations, equipment maintenance, and routine manufacturing support activities
• Lead manufacturing runs, mentor junior team members, and contribute to continuous improvement initiatives

What do we offer?

At Immatics, We Believe In Investing In Our Team’s Health, Safety And Well-being. Here’s What You Can Expect If You Join Immatics

Comprehensive Benefits

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
• 12 company paid holidays
• 7 days of sick time100% employer-paid life insuranceup to at 1x annual salary, up to one hundred thousand dollars
• 100% employer-paid short- and long-Term disability coverage
• 401(k) with immediate eligibilityand company match…
• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
• Partially paid parental leavefor eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard torace, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexualorientation, gender identity or expression, national origin, ancestry, age, marital status, disability, geneticinformation, veteran status, or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at [e-mail].

Work Authorization

Applicants must be authorized to work in the United States without the need for current or future sponsorship. Visa sponsorships may be available for certain roles.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.