Senior Manager, R&D Accounting – Biotech

Avalo Therapeutics, Inc.; Northern (KY); Hybrid; USD 110,000 - 160,000; Full time

Job summary

Avalo Therapeutics, Inc. is seeking a Senior Manager, Research & Development (R&D) Accounting to lead the accounting and financial reporting for the company’s R&D activities, including clinical trial costs, CROs, and CMC expenditures.

This role partners with Clinical Operations and FP&A to ensure timely, accurate reporting and strong internal controls. The ideal candidate has deep biotechnology R&D accounting experience, a solid general ledger background, and advanced Excel and ERP system

Qualifications

• Bachelor’s degree in Accounting or Finance required.
• CPA preferred but not required.
• MBA or Master’s degree is a plus.
• 8+ years of progressive accounting experience, including at least 5 years within publicly traded biotechnology or life sciences organizations.
• Extensive experience supporting clinical-stage biotechnology companies.
• Strong background in General Ledger accounting and monthly close.
• Demonstrated expertise in R&D accounting, including: Clinical trial accruals, CRO accounting, Clinical vendor management, Investigator payments, CMC accounting.
• Strong understanding of U.S. GAAP.
• Experience supporting external audits and internal controls
• Biotech/Pharmaceutical industry experience preferred
• Advanced Microsoft Excel skills, including complex formulas, pivot tables, and data analysis.
• Experience with ERP systems (Intacct preferred) and financial reporting tools.
• Ability to analyze large datasets and translate findings into actionable business insights.
• Strong project management and organizational skills with the ability to manage multiple priorities and deadlines.
• Excellent verbal and written communication skills and proven ability to partner with cross-functional teams.
• Ability to work independently in a fast-paced, publicly traded biotechnology environment.

Responsibilities

• Lead the monthly accounting and close process for all R&D activities.
• Own the monthly R&D accrual process, including vendor outreach and complex journal entries.
• Prepare and review journal entries, reconciliations, and schedules for R&D costs.
• Serve as the primary accounting partner to Clinical Operations, Clinical Development, CMC, Program Management, FP&A, and external vendors.
• Prepare R&D analyses and reporting for monthly, quarterly, and annual close.
• Prepare complex balance sheet reconciliations and account analyses.
• Analyze financial results, investigate variances, and ensure complete records.
• Assist with quarterly and annual financial reporting requirements.
• Collaborate with FP&A during budgeting, forecasting, and variance analysis.
• Review contracts and vendor agreements to support accounting treatment and accrual methodologies.
• Build strong relationships with internal stakeholders and external vendors.
• Continuously improve R&D accounting processes and software implementations.
• Develop documentation supporting accounting policies, procedures, and internal controls; assist with SOX readiness and audits.

Skills

R&D accounting

General Ledger

U.S. GAAP

Analytical skills

Cross-functional collaboration

Excel (pivot tables)

ERP systems (Intacct)

Financial reporting tools

Project management

Communication skills

Independent work

Education

Bachelor’s degree in Accounting or Finance

CPA preferred

MBA or Master’s degree

Tools

Intacct

ERP systems

Financial reporting tools

Job description

Avalo Therapeutics, Inc. is seeking a Senior Manager, Research & Development (R&D) Accounting to lead the accounting and financial reporting for the company’s R&D activities, including clinical trial costs, CROs, and CMC expenditures.

This role partners with Clinical Operations and FP&A to ensure timely, accurate reporting and strong internal controls. The ideal candidate has deep biotechnology R&D accounting experience, a solid general ledger background, and advanced Excel and ERP system