Senior LNP Analytical Scientist

Bristol Myers Squibb; Cambridge (MA); On-site; USD 87,000 - 105,000; Full time

Benefits offered by this job

Flexible Time Off

11 paid holidays

Paid vacation

Job summary

At Bristol Myers Squibb in Cambridge, MA, we seek a Senior Associate Scientist for LNP analytical testing. You will perform ELISA, HPLC, and other assays supporting research and process development, with strict GLP adherence.

You will analyze data, prepare reports, and help optimize methods under senior guidance, while ensuring safety and regulatory compliance in a collaborative, fast-paced setting.

Qualifications

• Bachelor’s degree in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or related scientific discipline.
• 1–5 years of hands-on laboratory experience, preferably with RNA and/or LNPs including academic research, internships, or industry roles.
• Proficiency with ELISA, Western blotting, cell-based assays, UV-Vis spectroscopy, or qPCR.
• Proficiency with HPLC operations, including method execution, column management, and chromatography data system use (e.g., Empower, OpenLabs, Chromeleon). Experience or familiarity with mass spectrometry is a plus.
• Familiarity with RNA characterization techniques (e.g., SEC, CE, RT-PCR, RNAseq).
• Demonstrated ability to manage multiple priorities in a fast-paced environment while maintaining accuracy and attention to detail.
• Demonstrated ability to analyze data and present results to the team and the larger research community.
• Familiarity with ICH guidelines, GLP/GMP principles, and regulatory submission requirements.
• Experience with LIMS and Benchling is a plus.
• Experience with bioanalytical method validation (e.g., per FDA or EMA guidelines).
• Working knowledge of statistical analysis tools (e.g., GraphPad Prism, JMP, or Excel-based analysis).

Responsibilities

• Perform routine analytical assays including ELISA, HPLC, and other analytical methods in support of research, process development, stability, and quality control activities
• Execute and document laboratory experiments according to established SOPs, protocols, and GLP standards
• Analyze, interpret, and summarize experimental data with accuracy; prepare clear and concise lab reports and technical summaries
• Maintain laboratory equipment including calibration, troubleshooting, and coordination with vendors for preventive maintenance
• Prepare reagents, buffers, and standards required for analytical testing; manage inventory of laboratory consumables and supplies
• Support method development and optimization efforts under the guidance of senior scientists
• Ensure compliance with all safety regulations, environmental health and safety (EHS) guidelines, and BMS corporate policies
• Contribute to cross-functional teams, collaborating with colleagues in research, process development, and formulations

Skills

ELISA

Western blotting

Cell-based assays

UV-Vis spectroscopy

qPCR

HPLC operations

Mass spectrometry

RNA characterization

Data analysis

Regulatory knowledge

Education

Bachelor’s degree in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or related scientific discipline

Tools

LIMS

Benchling

Empower

OpenLabs

Chromeleon

Job description

At Bristol Myers Squibb in Cambridge, MA, we seek a Senior Associate Scientist for LNP analytical testing. You will perform ELISA, HPLC, and other assays supporting research and process development, with strict GLP adherence.

You will analyze data, prepare reports, and help optimize methods under senior guidance, while ensuring safety and regulatory compliance in a collaborative, fast-paced setting.