LNP Analytical Scientist, Drug Delivery Formulations

Commonwealth Sciences, Inc.; Boston (MA); Sur place; USD 85 000 - 125 000; Plein temps

Résumé du poste

Commonwealth Sciences, Inc. in Boston, MA seeks a hands-on analytical scientist to design and execute assays for drug substances, products and LNP formulations.

You will characterize nanoparticles with DLS, PALS, and chromatographic techniques, generate data to support discovery and preclinical programs, and collaborate with formulation and process development teams. You will independently plan experiments, troubleshoot analytical challenges, document results, and help transfer methods to

Qualifications

• BS degree in Chemistry, Biochemistry, Pharmaceutical Sciences, Formulation Science, Chemical Engineering, Bioengineering, or related discipline with approx. 3–5 years lab experience; or MS with approx. 1–3 years experience.
• Industry experience in biotech/pharma/drug delivery strongly preferred.
• Hands-on experience characterizing LNPs, lipid nanoparticles, liposomes, or other nanoparticle delivery systems.
• Experience with analytical techniques such as DLS, PALS, UPLC/HPLC, SEC, IP-RP, UV/CAD, NanoAnalyzer, pH, osmolality, or comparable methods.
• Practical understanding of formulation development and analytical characterization of LNPs or other drug delivery systems.
• Experience with aseptic lab practices and mammalian cell culture is a plus.
• Ability to independently plan and execute experiments while managing multiple priorities in a fast-paced environment.

Responsabilités

• Design, develop, optimize, and execute analytical assays for drug substances, products, and LNP formulations.
• Characterize LNP formulations using DLS, PALS, UPLC/HPLC, SEC, IP-RP, UV/CAD, pH and osmolality.
• Generate and evaluate data to assess LNP quality, formulation, and product performance.
• Collaborate with cross-functional groups to coordinate experiments and set priorities.
• Independently conduct lab studies, interpret results, troubleshoot, and report conclusions.
• Maintain accurate lab records, notebooks, and protocols per procedures.
• Identify opportunities to improve analytical methods, approaches, and workflows.
• Assist with development and transfer of methods to CRO/CDMO partners.
• Prepare and maintain reagents, standards, controls for testing.
• Contribute to lab operations including equipment maintenance, calibration, and safety.

Connaissances

Experiment planning

Prioritization

Cross-functional collaboration

Troubleshooting

Technical reporting

Formation

Bachelor's degree in Chemistry, Biochemistry, Pharmaceutical Sciences, Formulation Science, Chemical Engineering, Bioengineering, or related field

Master's degree (MS) with 1–3 years experience

Outils

DLS

PALS

UPLC/HPLC

SEC

IP-RP

UV/CAD

NanoAnalyzer

Description du poste

Commonwealth Sciences, Inc. in Boston, MA seeks a hands-on analytical scientist to design and execute assays for drug substances, products and LNP formulations.

You will characterize nanoparticles with DLS, PALS, and chromatographic techniques, generate data to support discovery and preclinical programs, and collaborate with formulation and process development teams. You will independently plan experiments, troubleshoot analytical challenges, document results, and help transfer methods to