Senior Histotechnologist: Tissue Prep for Genomic Sequencing

Natera; San Carlos (CA); On-site; USD 116,278,000 - 145,334,000; Full time

Benefits offered by this job

Long-term equity awards

401(k) with company match

Generous paid time off

Wellness and work-life benefits

Job summary

Natera is seeking a Histology Technician to support the tissue preparation for our Signatera whole exome/genome sequencing labs in California. You will handle histology tasks, slide preparation, dissection, and workflow support, ensuring accuracy and adherence to TAT goals.

The role includes validations, reagent qualifications, and potential supervision responsibilities depending on experience. A strong focus on quality and training is required.

Qualifications

• Associate’s or higher in histology or a related biological science.
• 1+ years of histology experience or training within the past 5 years, or 9-month histotechnician training.
• Bachelor’s or higher with biology/chemistry coursework and 1+ year histology experience or equivalent training.

Responsibilities

• Perform histological preparations for tissue WES/WGS laboratory with accuracy.
• Prepare tissues and stained slides; macrodissection and support workflows.
• Independently handle testing, reagent and equipment prep after training.
• Participate in validations and reagent qualifications.
• Monitor case management and ensure timely processing within TAT goals.
• Assist EH&S initiatives and SOP updates.
• May supervise and train team members as needed.
• Document corrective actions for protocol deviations.

Skills

Histology

Tissue preparation

Quality control

Documentation

Team communication

Training

Equipment troubleshooting

Education

Associate degree in Histotechnician or related science

Bachelor’s degree in chemical/biological sciences (with biology/chemistry coursework)

Tools

Google Suites

Microsoft Office

Laboratory equipment operation

Job description

Natera is seeking a Histology Technician to support the tissue preparation for our Signatera whole exome/genome sequencing labs in California. You will handle histology tasks, slide preparation, dissection, and workflow support, ensuring accuracy and adherence to TAT goals.

The role includes validations, reagent qualifications, and potential supervision responsibilities depending on experience. A strong focus on quality and training is required.