Senior Downstream Bioprocess Modeling Scientist

Merck & Co.

Boston (MA)

Hybrid

USD 142,000 - 224,000

Full time

3 days ago
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Benefits offered by this job

Medical benefits
401(k)
Paid time off

Job summary

Merck & Co. in the Boston area is seeking an Associate Principal Scientist to lead mechanistic downstream modeling within the DSCS Digital Technologies group.

You will build and calibrate chromatography models, guide resin and process design, and collaborate with DSP scientists and engineers to translate model outputs into manufacturing decisions. The role requires deep expertise in preparative chromatography, numerical simulation, and mentoring, with a path to shape modeling standards and

Qualifications

  • Ph.D. with 3+ years of industrial/pharmaceutical experience.

Responsibilities

  • Build, calibrate, and validate mechanistic chromatography models.

Skills

Mechanistic modeling
CARET/GoSilico
Numerical simulation
Downstream chromatography
Parameter estimation
Mentoring

Education

Ph.D. in Chemical Engineering/Bioengineering or related
MS in Chemical Engineering/Bioengineering or related
BS in Chemical Engineering/Bioengineering or related

Tools

CADET
GoSilico
Python

Job description

Merck & Co. in the Boston area is seeking an Associate Principal Scientist to lead mechanistic downstream modeling within the DSCS Digital Technologies group.

You will build and calibrate chromatography models, guide resin and process design, and collaborate with DSP scientists and engineers to translate model outputs into manufacturing decisions. The role requires deep expertise in preparative chromatography, numerical simulation, and mentoring, with a path to shape modeling standards and

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