Senior Director: AI-Ready Data Architecture for Discovery

Eli Lilly and Company; Indianapolis (IN); On-site; USD 194,000 - 339,000; Full time

Benefits offered by this job

Company bonus

401(k) and pension

Medical/Dental/Vision

Flexible benefits

Paid time off

Job summary

Lilly, headquartered in Indianapolis, seeks a Senior Director, Data Architecture to define the scientific information architecture powering AI-native drug discovery across Molecular Discovery.

As a senior leader within Architecture4Insight, you will establish the architectural vision, standards, and roadmap that transform scientific data into a strategic asset for discovery scientists, computational researchers, and autonomous AI agents.

Qualifications

• MS or PhD in Computer Science, Data Science, Bioinformatics, Computational Biology, Information Science, or related STEM field.
• Ph.D. with 8+ years or MS with 12+ years of experience in scientific informatics, data architecture, platform architecture, data engineering, or related technical disciplines.
• Deep expertise spanning data modeling, metadata management, ontology engineering, semantic technologies, knowledge graphs, scientific data platforms, and AI-ready data ecosystems.

Responsibilities

• Define and drive the scientific information architecture strategy and implementation.
• Establish standards and architectural principles for data modeling, metadata management, semantic interoperability, ontology governance, and FAIR data implementation.
• Develop roadmaps for scientific data platforms, metadata capabilities, knowledge systems, and AI-ready data assets.
• Serve as a senior technical leader and architecture authority across Data Foundry initiatives.
• Mentor architects, engineers, and scientific informatics professionals.
• Personally contribute to architecture design, technology evaluation, and solution development for high-priority initiatives.
• Lead a team of Data Architects supporting scientific information architecture across Molecular Discovery.
• Foster a culture of technical excellence, innovation, and scientific partnership.
• Promote architectural consistency, knowledge sharing, and adoption of best practices across Architecture4Insight.
• Develop and maintain reference architectures, design patterns, and architectural standards.
• Measure and improve platform interoperability, metadata quality, discoverability, and architecture adoption across Molecular Discovery.
• Help shape the long-term evolution of Data Foundry's scientific data ecosystem.
• Enable unified discovery and exploration of scientific knowledge across molecules, targets, pathways, assays, experiments, structural biology data, and AI-generated insights.
• Drive adoption of semantic technologies including RDF, OWL, SPARQL, and modern knowledge representation frameworks.
• Drive consistency in metadata harmonization, ontology integration, and semantic interoperability across scientific platforms.

Skills

Data architecture

Technical leadership

Mentoring

Knowledge graphs

Semantic technologies

Communication

Education

Ph.D. in Computer Science, Data Science, Bioinformatics, or related STEM field

Tools

Databricks

Snowflake

Spark

Delta Lake

Neo4j

Amazon Neptune

Cloud platforms

Job description

Lilly, headquartered in Indianapolis, seeks a Senior Director, Data Architecture to define the scientific information architecture powering AI-native drug discovery across Molecular Discovery.

As a senior leader within Architecture4Insight, you will establish the architectural vision, standards, and roadmap that transform scientific data into a strategic asset for discovery scientists, computational researchers, and autonomous AI agents.