Senior Control Systems & IT/OT Operations Lead

Roche

South San Francisco (CA)

On-site

USD 150,000 - 279,000

Full time

14 days+

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Job summary

Genentech in South San Francisco seeks a Control Systems and Infrastructure Support Lead to drive the site control systems strategy, oversee 24/7 support for manufacturing computer systems, and collaborate closely with IT and operations teams.

The role requires a strong background in regulated environments, with 10+ years in control systems engineering, hardware experience, and familiarity with OT cybersecurity. A leadership mindset and cross‑functional collaboration are essential.

Qualifications

Bachelor’s degree in Engineering, Computer Science, IT or related field.
At least 10 years systems engineering in control systems, preferably in a regulated industry.
24x7 on‑call support to meet business continuity requirements.
Experience with control system hardware (controllers, power supplies, I/O).
OT cybersecurity familiarity and Purdue Model understanding are a plus.
Experience with antivirus and backup applications for control systems.

Responsibilities

Provide leadership for site systems engineers and system owners.
Maintain the Control Systems strategy and roadmap with business partners, IT and vendors.
Oversee 24/7 technical support for Manufacturing Computerized Systems (GMP and non-GMP).
Drive reliability, lifecycle management, and continuous improvement of site control systems.
Collaborate with site operations and IT teams as primary technical advisor.