Senior Chemist

Quadratic 3D, Inc.; Boston (MA); On-site; USD 85,000 - 130,000; Full time

Job summary

A leading company in 3D printing technology is seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for innovative printing resins. This role involves rapid exploration of chemical space and collaboration with analytical chemists to develop high-throughput capabilities. Ideal candidates will have a strong background in synthetic and physical organic chemistry, with a proven publication record.

Qualifications

• Strong expertise in synthetic and physical organic chemistry.
• Experience designing multi-step synthetic routes.
• Robust publication record in relevant fields.

Responsibilities

• Design and troubleshoot small molecule synthetic routes.
• Characterize lead candidates using various analytical techniques.
• Collaborate to establish structure-property relationships.

Skills

Synthetic chemistry

Physical organic chemistry

Data analysis

Project management

Collaboration

Education

PhD in Organic Chemistry

BS in Chemistry with 5+ years experience

Tools

UPLC

NMR

UV/Vis spectroscopy

IR spectroscopy

Mass spectrometry

Job description

Description

We are seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for next-generation 3D printing resins. Similar to a drug discovery role, this position involves rapid exploration of chemical space through organic synthesis to develop structure-property relationships. Our feedback loops take only days rather than months or years, involving diverse photochemistry. This role is ideal for synthetic chemists with a passion for physical organic chemistry. Our process uses small amounts of each lead candidate, so synthetic creativity is not limited by scalability concerns typically associated with materials applications.

Responsibilities

• Design, refine, and troubleshoot small molecule synthetic routes, focusing on divergent or modular approaches to rapidly generate lead candidates.
• Characterize lead candidates via UPLC, NMR, UV/Vis, IR spectroscopy, and mass spectrometry.
• Contribute to developing high-throughput analytical capabilities, small molecule databases, and virtual libraries.
• Collaborate with analytical chemists and chemical engineers to establish structure-property relationships in formulations containing lead candidates.

Minimum Qualifications

• PhD in Organic Chemistry or BS in Chemistry with 5+ years of experience in a small molecule discovery role.
• Strong expertise in synthetic and physical organic chemistry, demonstrated through publications and activities.
• Experience designing and executing multi-step synthetic routes.
• Proficiency with modern computing and data analysis tools relevant to synthetic chemistry.
• Excellent communication, organizational, and time management skills.
• Ability to independently drive projects from conception to completion.
• Strong collaboration and teamwork skills.
• Robust publication record, both as lead author and contributor.

Preferred Qualifications

• Expertise in photochemistry and/or radical chemistry.
• Experience with synthesis of heterocyclic and extended aromatic systems relevant to organic (opto)electronics. Familiarity with cheminformatics and computational chemistry tools (e.g., DFT).

Additional Information

• Travel: Occasional travel may be required.
• Location: Boston, Massachusetts

We value diversity and are an Equal Opportunity Employer.