Senior Analytical Chemist

Diasome Pharmaceuticals, Inc.; Boston (MA); On-site; USD 70,000 - 100,000; Full time

Job summary

An established industry player is seeking a Senior Analytical Chemist to join their dynamic team in the Boston area. This role involves crucial responsibilities such as sampling, testing, and method development in a GMP-regulated environment. The ideal candidate will have a strong background in analytical and formulation chemistry, with proficiency in key analytical equipment like HPLC and UV. This is a fantastic opportunity to contribute to innovative projects in the biotechnology sector while enjoying a competitive salary and benefits package, including potential stock options. If you're passionate about making a difference in the pharmaceutical landscape, this role is for you.

Benefits

Competitive Salary

Stock Options

Health Benefits

Professional Development Opportunities

Qualifications

• Degree in chemistry, chemical engineering, or related fields required.
• Experience in GMP environments and analytical chemistry essential.

Responsibilities

• Conduct sampling and testing of raw materials and finished products.
• Develop analytical methods and validate protocols for new formulations.

Skills

Analytical Chemistry

Formulation Chemistry

Synthetic Chemistry

GMP Compliance

HPLC

Method Development

Data Analysis

Communication Skills

Problem-Solving

Time Management

Education

Undergraduate Degree in Chemistry

Graduate Degree in Chemistry or Related Field

Tools

HPLC Software (Chromeleon, ChemLab)

Microsoft Office

Job description

Senior Analytical Chemist (Quality Control)

Essential Requirements: Undergraduate and graduate degrees in chemistry, chemical engineering, physics, or material sciences. Experience in analytical, formulation, and synthetic chemistry. Experience in a GMP (or similarly regulated) laboratory. Pharmaceutical and/or biotechnology industry experience required.

Responsibilities:

1. Sampling and testing of raw materials, intermediates, and finished products using current pharmacopoeias, any associated ‘wet’ chemistry, and instrumental techniques (HPLC, UHPLC, IR, UV, CAD), as appropriate.
2. Method development for material characterization (peptide, small molecule, and nanoparticle).
3. Analyze results of experimental studies and write reports for both corporate records and regulatory bodies.
4. Providing reports, including analytical reports (for raw materials and finished products), Certificates of Analysis (CoA), process development reports, method development reports, and stability reports.
5. Knowledge of common formulation techniques and methodologies.
6. Knowledge of common HPLC softwares (Workstation, Chromeleon, ChemLab).
7. Method Development and Tech Transfer.
8. Developing and/or performing all formulation requirements on new formulas; includes creation of theoretical formulation, bench mix development, product description/formulation sheet, lab tests, stability testing/monitoring, color verification, etc.
9. Prepare and execute analytical method validation protocols and studies.
10. Prepare and execute stability studies on various materials.
11. Writing of briefs and reports summarizing data and conclusions.
12. Stability testing of products for new formulations and ongoing stability trials, using physical (pH, viscosity) and instrumental (HPLC, UV) techniques as appropriate.
13. Writing analytical specifications using current pharmacopoeias and ICH guidelines and reviewing existing analytical specifications.
14. Assist in verification studies as required.
15. Inventory monitoring.
16. Calibrating analytical equipment as required, working with vendors to maintain service contracts for equipment.
17. Ensuring procedures are carried out carefully and accurately to eliminate errors.
18. Ensuring good relations and communication within the team.
19. Ability to explain analytical work and progress to other personnel or trainees.
20. Observing and complying with GMP, Health and Safety Policies, and SOPs.
21. Undertaking any other duties within the department or other departments as requested by the manager, with proper training and understanding.

Person Profile:

• Highly proficient in the use of key analytical equipment (HPLC, UHPLC, IR, UV) and testing of finished products.
• Demonstrable track record and skills/experience in a similar position at a similar level.
• Experience working in a GMP environment.
• Good IT skills, e.g., Microsoft Office.
• Credible and confident communicator (written and verbal) at all levels.
• Meticulous attention to detail and high standards.
• Excellent planning, organizational, and time management skills.
• Ability to work accurately under pressure, adhering to deadlines.
• Strong analytical and problem-solving skills, with good math skills.
• Self-motivated, proactive, and committed to learning and development.

Location: Boston Metropolitan Area

Salary and Benefits: Commensurate with experience. Competitive salary and benefits, with potential stock options.

Additional Information

• Seniority level: Mid-Senior level
• Employment type: Full-time
• Job function: Research, Analyst, and Information Technology
• Industries: Biotechnology