Senior Cell Culture & Line Development Scientist (Hybrid)

Prellis Biologics; Berkeley (CA); Hybrid; USD 90,000 - 120,000; Full time

Benefits offered by this job

Group medical, dental, and vision

Life and disability insurance

401(k) plan

Holiday package including a 1+ week冬季休

Job summary

Prellis Biologics in Berkeley, CA is seeking a Senior Research Associate, Cell Culture/Cell Line Development, to maintain, scale, and develop mammalian cell lines for biologics discovery. The role involves hands-on laboratory work, data analysis, and collaboration with cross-functional teams to advance antibody screening.

You will perform aseptic culture across CHO and HEK293 lines, support transfection and clone screening, and contribute to in vitro assays.

Qualifications

• B.S. in molecular biology, chemistry, immunology, biotechnology, or related life science field.
• 2+ years of relevant laboratory experience.
• 1-2 years hands-on mammalian cell culture experience, industry preferred.
• Familiarity with cell line development techniques (stable and transient transfection, clone selection, characterization).
• Strong organizational and time-management skills.
• Ability to work independently and in a collaborative team.
• Experience with small-scale bioreactor systems is a plus.

Responsibilities

• Perform aseptic mammalian cell culture across multiple cell lines in parallel (e.g., CHO, HEK293).
• Maintain, passage, expansion, and cryopreservation of cell lines to ensure a reliable supply of high-quality cells for downstream applications.
• Support cell line development workflows, including transfection, clone screening, and selection.
• Contribute to cell-based in vitro assay execution to support antibody screening and downstream characterization efforts.
• Maintain meticulous experimental records and effectively communicate findings in internal meetings.
• Contribute to process optimization for improved productivity and product quality.

Skills

Mammalian cell culture

Aseptic technique

Transfection/clone screening

Data analysis

Independent / collaborative work

Education

B.S. in Molecular Biology, Chemistry, Immunology, Biotechnology, or related life science field

Tools

Small-scale bioreactor systems

Job description

Prellis Biologics in Berkeley, CA is seeking a Senior Research Associate, Cell Culture/Cell Line Development, to maintain, scale, and develop mammalian cell lines for biologics discovery. The role involves hands-on laboratory work, data analysis, and collaboration with cross-functional teams to advance antibody screening.

You will perform aseptic culture across CHO and HEK293 lines, support transfection and clone screening, and contribute to in vitro assays.