Senior Cell Culture & Line Development Scientist

Prellis Biologics, Inc; Berkeley (CA); Hybrid; USD 90,000 - 125,000; Full time

Benefits offered by this job

Remote work options

Flexible work models

Job summary

Prellis Biologicś seeks a highly motivated Research Associate - Senior Research Associate, Cell Culture/Cell Line Development to join the Antibody Screening team. You will maintain and scale mammalian cell lines (e.g., CHO, HEK293) for biologics discovery and contribute to cell-based assays with close cross-functional collaboration.

The role involves hands-on lab work, data analysis, record-keeping, and process optimization to improve productivity and product quality.

Qualifications

• BS in life sciences with 2+ years relevant experience.
• 1–2 years hands-on mammalian cell culture; aseptic technique required.
• Familiarity with cell line development techniques (stable/transient transfection, clone selection).
• Strong organizational and time management skills in a fast-paced environment.
• Ability to work independently and in a cross-functional team.
• Experience with small-scale bioreactor systems is a plus.

Responsibilities

• Perform aseptic mammalian cell culture across multiple lines (e.g., CHO, HEK293).
• Maintain, passage, expansion, and cryopreserve cell lines for downstream use.
• Support cell line development workflows, including transfection and clone screening.
• Contribute to cell-based in vitro assays for antibody screening and characterization.
• Maintain meticulous experimental records and communicate findings in meetings.
• Assist process optimization for productivity and product quality.

Skills

Mammalian cell culture

Aseptic technique

Transfection

Clone screening

Data analysis

Team collaboration

Education

Bachelor's degree in Molecular Biology or related field

Tools

Small-scale bioreactor systems

Job description

Prellis Biologicś seeks a highly motivated Research Associate - Senior Research Associate, Cell Culture/Cell Line Development to join the Antibody Screening team. You will maintain and scale mammalian cell lines (e.g., CHO, HEK293) for biologics discovery and contribute to cell-based assays with close cross-functional collaboration.

The role involves hands-on lab work, data analysis, record-keeping, and process optimization to improve productivity and product quality.