Senior Bioprocess Engineer

MilliporeSigma; Burlington (MA); On-site; USD 126,000 - 189,000; Full time

Benefits offered by this job

Health insurance

PTO

Retirement contributions

Other perquisites

Job summary

MilliporeSigma in Massachusetts is seeking a Senior Bioprocess Engineer to advance bioprocessing technologies supporting the development of biologics. You will design and execute laboratory experiments to evaluate prototypes and applications, translating insights into scalable process solutions.

You will define process control strategies, optimize recipes, monitor industry trends, and present findings across teams. Travel domestically and internationally may be required.

Qualifications

• PhD/MS/BS in Biological or Chemical Engineering or related field with bioprocess development experience.
• Experience setting up and executing downstream unit operations (Chromatography, NFF, TFF).
• Strong data modeling, DoE, and statistical analysis skills.

Responsibilities

• Design and execute lab experiments to evaluate new technologies, prototypes, and applications.
• Define process control strategies and develop optimized recipes and methods.
• Publish findings through internal/external publications and presentations; guide cross-functional decisions.

Skills

Bioprocess engineering

Downstream processing

Lab experimentation

Analytical skills

Education

PhD in Biological or Chemical Engineering or related field with 2+ years bioprocess development

MS in Biological or Chemical Engineering or related field with 3+ years bioprocess development

BS in Biological or Chemical Engineering or related field with 5+ years bioprocess development

Tools

Laboratory automation platforms

GMP environments

Job description

Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

Your Role

• As a Senior Bioprocess Engineer at MilliporeSigma, you will play a pivotal role in advancing the performance and application of cutting‑edge bioprocessing technologies that directly support the development of life‑saving biologics. Working as a key member of a cross‑functional team, you will design and execute laboratory experiments to evaluate new technologies, product prototypes, and application scenarios, translating scientific insight into real‑world process solutions.
• You will define process control strategies and develop optimized recipes and methods that set the standard for product performance. Drawing on your deep expertise in downstream processing, you will monitor industry trends, engage with the scientific community, and represent the organization at conferences to stay at the forefront of bioprocessing innovation.
• You will communicate your findings through high‑quality internal and external publications, application notes, and presentations, establishing yourself as a trusted technical authority. By managing stakeholder relationships and guiding cross‑functional decisions, you will directly shape the strategic direction of the team and contribute to outcomes that matter for science, for customers, and for patients worldwide.

Who You Are

Basic / Minimum Qualifications:

• Experience setting up and executing downstream unit operations, including Chromatography, Normal Flow Filtration, and Tangential Flow Filtration (TFF).
• Prior experience in analytical methods and high‑throughput platforms in the context of downstream process development.
• PhD in Biological or Chemical Engineering or a related discipline and 2 or more years of experience in bioprocess development, OR a Master of Science in Biological or Chemical Engineering or a related discipline and 3 or more years of experience in bioprocess development, OR a Bachelor of Science in Biological or Chemical Engineering or a related discipline and 5 or more years of experience in bioprocess development.

Preferred Qualifications

• Hands‑on biotechnology industry experience, including TFF and Depth Filtration.
• Strong problem‑solving and analytical skills, including data modeling, Design of Experiments (DoE), and statistical analysis.
• Experience with laboratory automation platforms.
• Familiarity with Good Manufacturing Practice (GMP) environments.
• Excellent written and verbal communication skills, including the ability to produce application notes, technical reports, and poster presentations.
• Proven ability to collaborate effectively across teams and with external stakeholders including customers and vendors.
• Willingness to travel domestically and internationally as required.

Base Pay Range for this position: $ 126,100 – 189,100 $

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job‑related factors. Position may be eligible for sales or performance‑based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites.

What we offer:

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!