Senior Automation and Manufacturing Systems Engineer

Amgen; Holly Springs (MS); On-site; USD 115,000 - 156,000; Full time

Job summary

Amgen in the United States is seeking a Senior Manufacturing Systems Engineer (Automation - PLC) to provide technical leadership for automation engineers supporting the new drug substance plant operations. You will work with F&E Automation to deliver robust automation, integrate DeltaV, Allen-Bradley, and Siemens platforms, and ensure data integrity and compliance in a GxP environment.

The role emphasizes problem solving, lifecycle management, and cross‑functional collaboration to optimize

Qualifications

• Bachelor's degree in engineering or related field.
• Master's degree preferred for advanced roles.
• Strong knowledge of GMP/21 CFR Part 11 requirements.

Responsibilities

• Develop and maintain PLC-based automation solutions.
• Integrate with Emerson DeltaV system and SCADA.
• Lead control panel/HMI layout and design work.
• Collaborate with SMEs to convert requirements into automation.
• Support validation and documentation in a GMP environment.
• Lead continuous improvement for equipment and utilities.

Skills

PLC design

Rockwell Automation

Siemens

GMP knowledge

System integration

Education

Bachelor's Degree in Engineering

Master's Degree in Engineering

Tools

Allen-Bradley

Siemens

Emerson DeltaV

SCADA

Job description

Amgen in the United States is seeking a Senior Manufacturing Systems Engineer (Automation - PLC) to provide technical leadership for automation engineers supporting the new drug substance plant operations. You will work with F&E Automation to deliver robust automation, integrate DeltaV, Allen-Bradley, and Siemens platforms, and ensure data integrity and compliance in a GxP environment.

The role emphasizes problem solving, lifecycle management, and cross‑functional collaboration to optimize