Senior Automation Engineer – BAS & PLC (GMP)

amgen; Holly Springs (NC); Hybrid; USD 115,000 - 156,000; Full time

Benefits offered by this job

Total Rewards Plan

Stock-based incentives

Flexible work arrangements

Retirement & savings plan

Job summary

Amgen is seeking a Senior Manufacturing Systems Engineer specializing in automation to lead BAS/PLC systems for a cutting-edge drug substance facility. You will drive engineering efforts across design, start-up, and operational readiness, aligning with GMP requirements and project timelines.

Join a team advancing biotechnology with a focus on safety, quality and reliability. The role offers hands-on engineering leadership, cross-functional collaboration, and opportunities to influence

Qualifications

• Bachelor’s degree in Electrical Engineering or related field.
• Master’s degree with 2 years of relevant experience is preferred.
• GMP/biopharma automation knowledge and practice is required.
• Familiarity with 21 CFR Part 11 and GMP documentation is essential.
• Experience with building automation controls and PLC-based systems is expected.

Responsibilities

• Provide automation technical leadership for BAS/PLC systems.
• Collaborate with capital project teams on commissioning and qualification activities.
• Develop and maintain engineering documentation for validated systems.
• Support IV/ACO and QA validation in a GxP environment.
• Own Change Controls, CAPAs, and deviations for assigned systems.
• Lead FAT with vendors and ensure compliance with Amgen standards.

Skills

Automation leadership

PLC programming

BAS design

GxP knowledge

Data integrity

Education

Bachelor’s in Electrical Engineering

Master’s degree preferred

Tools

PLC systems

Field instrumentation

Job description

Amgen is seeking a Senior Manufacturing Systems Engineer specializing in automation to lead BAS/PLC systems for a cutting-edge drug substance facility. You will drive engineering efforts across design, start-up, and operational readiness, aligning with GMP requirements and project timelines.

Join a team advancing biotechnology with a focus on safety, quality and reliability. The role offers hands-on engineering leadership, cross-functional collaboration, and opportunities to influence