Senior Associate Scientist: Single-Cell Genomics & Cytometry

ALSAC

Memphis (TN)

On-site

USD 66,000 - 114,000

Full time

14 days+

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Job summary

ALSAC’s St. Jude Children’s Research Hospital seeks an Associate Scientist to operate within the Single Cell Genomics Core and Neurocytometry Core, advancing neural tissue single-cell sequencing and flow cytometry workflows.

The role involves design and optimization of high-parameter panels, instrument setup, and user training across platforms. The ideal candidate brings strong background in molecular biology and neuroscience, with hands-on experience in 10x Genomics Chromium and cytometry

Qualifications

Bachelor’s degree in a relevant scientific area.
7+ years of research experience; MS reduces to 5+; PhD 2+.
Experience leading and coordinating research projects.
Training experience for technicians and students.
Strong molecular, cellular biology and neuroscience background.

Responsibilities

Independently perform experiments using existing, modified, or newly developed techniques/protocols.
Accurately record experimental procedures and data.
Prepare and report results/data leading to posters, presentations, or publications.
Set up protocols using new or modified laboratory techniques and troubleshoot experiments independently.
Identify experimental data pertinent to the analysis problem; process, organize, and summarize data; report results.
Independently perform single-cell sample processing, including neural tissue/cell dissociation, viability assessment, and loading onto single-cell sequencing platforms (e.g., 10x Genomics Chromium).
Coordinate sample intake, quality control, and sequencing run scheduling for the Single Cell Genomics Core and communicate results and troubleshooting steps to investigators.
Establish, modify, and implement Standard Operating Procedures (SOPs) for routine maintenance and performance evaluation of flow cytometers and associated instrumentation.
Independently perform instrument setup, sample acquisition, calibration, alignment, troubleshooting; oversee instrument repair and service coordination.
Train technicians, students, and investigators on cytometry concepts, including instrument startup/shutdown, routine maintenance, sample acquisition, and basic data analysis.
Collaborate with investigators to develop, evaluate, and optimize multicolor flow cytometry assays, including high-parameter panels.
Perform regular cell sorting services and support users in developing technically sound, biologically relevant cytometry-based approaches.
Provide ongoing support for monitoring, maintenance, ordering, and purchasing of equipment and supplies as needed.
Perform other duties as assigned to meet the goals and objectives of the department and the institution.
Maintain regular and predictable attendance.