Scientist

Russell Tobin; San Diego (CA); On-site; USD 62,000 - 67,000; Full time

Job summary

Russell Tobin is partnering with a top biotechnology organization to identify a Scientist- LNP Formulation for an opportunity near San Diego, CA. The role is a long-term contract, onsite in San Diego, with 40 hours weekly.

The candidate will execute LNP/tLNP formulation and DoE-based screening to optimize nanoparticle formulations and processing. The ideal candidate has 5+ years in biopharma, with hands-on LNP formulation experience, analytical skills in DLS and zeta potential, and strong data

Qualifications

• Bachelor's degree in chemistry, biochemistry, chemical engineering or related discipline; 5+ years biopharma experience or Master's with 2+ years.
• 2+ years hands-on LNP formulation and encapsulation of nucleic acids (mRNA, siRNA, DNA).
• Proficiency with LNP characterization methods: DLS, zeta potential, Ribogreen.
• High proficiency in MS Excel; experience with JMP or Prism.

Responsibilities

• Execute and optimize LNP/tLNP formulation and characterization for in-vitro and in-vivo studies.
• Conduct DoE-based screening to optimize LNP compositions and processing.
• Collaborate with internal teams to fulfill formulation requests.
• Support early-stage formulation development including cryoprotection, scale-up and stability studies.
• Maintain detailed records of formulation activities and results.
• Analyze and present experimental data to the team.
• Support lab management tasks: inventory, supplies, buffers and autoclaving.

Skills

LNP formulation

DoE campaigns

Cross-functional collaboration

Data interpretation & presentation

Biopharma experience

Education

Bachelor's degree in chemistry/biochemistry/chemical engineering

Master's degree in related field

Tools

JMP

Prism

MS Excel

Job description

Russell Tobin is partnering with a top biotechnology organization to identify a Scientist- LNP Formulation for an opportunity near San Diego, CA.

Important Details:

• Long-term contract opportunity
• San Diego, CA- Fully Onsite
• Monday-Friday (40 hours/week)
• Pay range: $45-48.95/HR, depending on experience

Key Responsibilities:

• Execute and optimize the formulation and characterization of lipid nanoparticles (LNPs) or targeted lipid nanoparticles (tLNPs) encapsulating nucleic acids for in-vitro and in-vivo studies under the minor guidance of senior formulation scientists.
• Implement Design of Experiment (DoE) based screening campaigns to evaluate and establish optimal LNP compositions and processing parameters.
• Collaborate cross-functionally with internal teams to support and fulfill formulation requests.
• Support early-stage formulation development and downstream processing activities when needed, including cryoprotection, scale-up, and stability studies.
• Maintain detailed records documenting formulation activities and results.
• Analyze, interpret, and present experimental data to the formulation team.
• Contribute to routine lab management activities, including inventory tracking, supply ordering, buffer preparation, and autoclaving.

Must have qualifications:

• Bachelor’s degree in chemistry, Biochemistry, Chemical Engineering, or a related discipline with 5+ years of biopharma industry experience, OR a Master's degree with 2+ years of industry experience.
• LNP Expertise: Minimum of 2 years of hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids (mRNA, siRNA, or DNA).
• Analytical Skills: Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays.
• Software & Data: High proficiency in MS Excel is required; hands-on experience with statistical and data analysis software (e.g., JMP, Prism) is preferred.
• Core Competencies: Strong attention to detail, a track record of producing reproducible data, excellent organizational skills, and the ability to communicate effectively within a fast-paced team environment.
• Prior experience with targeted LNP preparation (mAb, Fab, ScFv, VHH coated LNP) and immune cell delivery is highly desirable.

For workers in the United States, PrideGlobal and it's affiliates offers eligible employee’s comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance and hospital indemnity), 401(k)-retirement savings, life & disability insurance, an employee assistance program, legal support, pet insurance and employee discounts with preferred vendors.

Equal Employment Opportunity PrideGlobal and it's affiliates are an equal opportunity employer. We do not discriminate on the basis of the race, religious creed, color, national origin, ancestry, physical disability, mental disability, reproductive health decision making, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, age, sexual orientation, veteran or military status, or any other characteristic protected by applicable federal, state, or local law.

Fair Chance Employment PrideGlobal and it's affiliates are a Fair Chance employer. We consider all qualified applicants, including those with criminal histories, in a manner consistent with applicable state and local Fair Chance laws and ordinances, including, the California Fair Chance Act and all applicable local Fair Chance ordinances.

Accommodations We are committed to providing reasonable accommodations to applicants and employees with disabilities. If you require a reasonable accommodation to participate in the application or interview process, or to perform the essential functions of this role, please contact us.

Only applicable for San Francisco Candidates Under the San Francisco Lactation in the Workplace Ordinance, we will provide written notice of lactation accommodation rights, and this notice will automatically be given upon hiring, any inquiry of parental leave or lactation accommodation.

Only applicable for Kentucky positions: For this type of employment, state law requires a criminal record check as a condition of employment. This applies to direct care staff (Examples: RN, LPN, Nurse Aides, Therapists) referred to Kentucky nursing facilities, assisted living communities, or long-term care facilities, in accordance with KRS 216.793.