Remote Senior Site Contracts Lead – Oncology

Syneos Health, Inc.; Plano (TX); Remote; USD 80,000 - 140,000; Full time

Job summary

Syneos Health is seeking a Senior Site Contracts Manager to lead budgeting, negotiation, and management of US clinical trial agreements for sponsor-dedicated programs. You will collaborate with academic institutions and internal teams to craft compliant contracts that protect the sponsor while enabling study execution.

Ideal candidates bring 4+ years of budgets and contract experience, strong negotiation and project leadership skills, and a solid understanding of clinical study timelines and

Qualifications

• 4+ years building budgets and contracts from templates.
• Direct experience negotiating with large academic institutions
• Ability to juggle priorities, lead projects, and deliver results under tight timelines
• Strong understanding of clinical study protocols, timelines, and site-related milestones (e.g., SIV)

Responsibilities

• Budgeting & Template Development: Build US site budget templates and study-specific budget language for Pharma & Vaccine clinical trials.
• Develop and refine templates to support consistency, compliance, and strategic study needs.
• Contract Negotiation & Risk Management: Lead direct negotiations with large academic institutions and other critical stakeholders.
• Draft and finalize clinical trial agreements that balance business objectives with legal and operational protections.
• Conduct due diligence checks—such as FMV assessments and site justification reviews—when initial offers are declined.
• Determine when requests require budget or language escalation and secure appropriate approvals.
• Project Leadership & Delivery: Prioritize and lead multiple contracting projects across several therapeutic areas (oncology experience strongly preferred).
• Proactively elevate risks, timeline impacts, or delays that could affect CTA execution.
• Tools, Systems & Communication: Demonstrate expert proficiency in Excel and clinical trial management systems.
• Communicate effectively in both written and verbal formats, incorporating feedback seamlessly.
• Maintain accurate and timely updates in departmental trackers and databases.
• Compliance, Collaboration & Continuous Improvement: Deepen and maintain knowledge of GCP, sponsor processes, SOPs, work instructions, and new technologies.
• Build strong working relationships with internal and external partners.
• Support and train additional team members as needed.
• Contribute to process improvement initiatives that simplify workflows and eliminate inefficiencies.
• Take on adhoc tasks and diverse projects with a solutionsoriented mindset.

Skills

Budgeting

Contract negotiation

Project management

Cross-functional collaboration

Communication

Education

Bachelor's degree

Tools

Excel

CTMS

Job description

Syneos Health is seeking a Senior Site Contracts Manager to lead budgeting, negotiation, and management of US clinical trial agreements for sponsor-dedicated programs. You will collaborate with academic institutions and internal teams to craft compliant contracts that protect the sponsor while enabling study execution.

Ideal candidates bring 4+ years of budgets and contract experience, strong negotiation and project leadership skills, and a solid understanding of clinical study timelines and