Remote Scientist II, QSP/QST Consulting & Modeling

Simulations Plus

United States

Remote

USD 110,000 - 130,000

Full time

17 hours ago

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Benefits offered by this job

Annual bonus

Flexible schedules

Health coverage

Generous vacation policy

Job summary

Simulations Plus stands as a global leader in model-informed and AI-accelerated drug development, offering remote work, flexible schedules, and generous vacation policy along with health coverage and an annual bonus.

The Scientist II will contribute to consulting projects using QSP/QST models, with MATLAB or THALES in a remote setting and opportunities across oncology, hepatology, metabolic, and inflammatory diseases.

Qualifications

2+ years of QSP/QST modeling experience or demonstration of the equivalent skill sets.
Proficiency in mathematics, dynamic systems, drug development.
General knowledge of relevant therapeutic areas, including clinical endpoints and underlying cell and molecular biology and/or biochemistry.
Experience with MATLAB, THALES, Julia, SimBiology, Monolix, GastroPlus, and/or C++ programming.
Experience with PBPK, PK, popPK and/or PKPD modeling.
Basic familiarity with large-language models and agentic AI.
Understanding of how to apply modeling and simulation for maximum impact.
Strong verbal and written communication skills.
Maintains a positive attitude while interacting with colleagues and clients.
Must be able to multitask and have good organizational skills.
Occasional travel for conferences, meetings, and training.

Responsibilities

Design, write, test, and use computer code to build and maintain the sub-model(s), representing core cellular, molecular, and/or biochemical processes in a given model
Represent compound pharmacodynamics (PD) and/or mechanism of action (MoA), including translating laboratory data into model parameters and curation of clinical data for calibration/validation
Learn and effectively utilize company agentic AI solutions for technical work
Contribute to the activities required for successful completion of all goals within consulting projects
Contribute (as time allows) to R&D efforts, including updating the "license-ready" versions of the various models and supporting ongoing development of QST models of liver injury (i.e., the DILI-sim consortium)
Combine technical and project management work, including components such as systems pharmacology modeling, software code development, and maintenance in designated software environments
Develop plans to complete all tasks and provide all deliverables within a time frame consistent with the services agreement signed with the sponsor
Schedule the necessary meetings including internal and external collaborators
Exert leadership in the areas of presentation and report preparation by exhibiting strong skills for effective presentations and reports, applying diligent scientific review, and being timely with execution and responses to feedback
Lead consulting projects, upon demonstrating the necessary technical and project management skills and availability of a suitable project
Participate in preparation and review of joint manuscripts between the company and the sponsor
Manage the effort expended for a given project to remain consistent with the resources allocated for the project per the signed contract
Publish work in scientific journals, with minimal review required by their supervisor, including documentation preparation, text development, figure development, and correspondence with editors and peer reviewers
Train others on QSP/QST and the various models
Other duties as assigned