Remote Fractional CMO – Neurodegeneration Leadership

Warman O'Brien; United States; Remote; USD 150,000 - 300,000; Part time

Job summary

Warman O’Brien is partnering with an innovative biotechnology company seeking an experienced Fractional Chief Medical Officer to provide strategic clinical development leadership across a neurodegeneration pipeline, with potential to transition to full-time executive.

This remote US role requires an MD with significant CNS drug development experience, and proven leadership at the CMO/VP level, with a track record in mid-to-late-stage programs and regulatory strategy.

Qualifications

• MD qualification with significant CNS/neuroscience drug development experience.
• Proven leadership in clinical development at senior levels (CMO/SVP/VP).
• Experience in venture-backed or smaller biotech environments is highly desired.
• Ability to operate in a lean, entrepreneurial setting.

Responsibilities

• Lead clinical development strategy across neurodegenerative indications, with a particular focus on dementia-related disorders.
• Provide strategic oversight of clinical programmes, including trial design, regulatory strategy and development planning.
• Work closely with the CEO and executive leadership team to advance key clinical and corporate milestones.
• Support investor discussions, fundraising activities and scientific due diligence.
• Provide medical and scientific leadership, collaborating with external experts, clinical partners and regulatory authorities.
• Contribute to long-term pipeline strategy and future clinical development opportunities.

Skills

MD, CNS drug development

CMO/VP leadership

Education

MD degree

Job description

Warman O’Brien is partnering with an innovative biotechnology company seeking an experienced Fractional Chief Medical Officer to provide strategic clinical development leadership across a neurodegeneration pipeline, with potential to transition to full-time executive.

This remote US role requires an MD with significant CNS drug development experience, and proven leadership at the CMO/VP level, with a track record in mid-to-late-stage programs and regulatory strategy.