Chief Medical Officer

ARTO; United States; Remote; USD 250,000 - 350,000; Part time

Job summary

A clinical-stage biotechnology company is seeking a Fractional Chief Medical Officer (CMO) specializing in Immunology and Allergy. The role involves providing leadership across clinical programs, designing clinical trials, collaborating with regulatory agencies, and guiding portfolio development. Ideal candidates will have a medical degree, strong expertise in immunology, and experience in clinical trial leadership. This is a part-time executive position supporting innovative, disease-modifying clinical programs.

Qualifications

• Deep expertise in Immunology and Inflammation; experience in Allergy preferred.
• Demonstrated leadership across multiple phases of clinical development.
• Comfortable operating in a fractional/part-time executive capacity.

Responsibilities

• Provide senior medical and clinical development leadership across immune-focused programs.
• Lead overall clinical development strategy with emphasis on late-stage readiness.
• Collaborate with regulatory affairs and support interactions with global regulatory agencies.
• Collaborate with regulatory affairs and engage with global authorities (FDA/EMA).
• Guide portfolio prioritization and development planning aligned with company goals.
• Support investigator engagement and external scientific collaborations.
• Contribute to senior-level clinical and development decision making.

Skills

Immunology

Leadership

Communication

Regulatory engagement

Communication skills

Program management

Education

Medical degree (MD or equivalent)

Job description

Position Title: Fractional Chief Medical Officer (CMO) – Immunology / Allergy

Location: United States (Remote)

Engagement: Fractional / Part-Time

Company Overview

Clinical-stage biotechnology company focused on immune modulation and inflammatory disease, with a core emphasis on allergic and immune-mediated conditions.

The company is advancing differentiated, disease-modifying clinical programs in Allergy, supported by deep immunology expertise and a strong translational foundation.

Key Responsibilities

• Provide senior medical and clinical development leadership across immune-focused and allergy programs
• Lead and evolve overall clinical development strategy, with particular emphasis on late-stage (Phase II / III) readiness
• Provide medical oversight for clinical trial design, including endpoint strategy, protocol development, and data interpretation
• Collaborate with regulatory affairs and support interactions with global regulatory agencies (e.g., FDA, EMA)
• Partner closely with Clinical Operations to support trial execution, CRO oversight, and operational feasibility
• Provide strategic guidance on portfolio prioritization and development planning in alignment with company objectives
• Support investigator engagement, key opinion leader (KOL) interactions, and external scientific collaborations
• Contribute to senior-level clinical and development decision making

Qualifications

• Medical degree (MD or equivalent) required
• Deep expertise in Immunology and Inflammation; experience in Allergy strongly preferred
• Demonstrated leadership across multiple phases of clinical development, including late-stage programs
• Prior experience supporting Phase IIb / III trials and registrational strategy
• Track record of engagement with US and/or ex-US regulatory authorities
• Comfortable operating in a fractional / part-time executive capacity within a clinical-stage biotech environment
• Strong communication skills with the ability to partner effectively across scientific, clinical, regulatory, and operational teams