CMO - Hematology & Rare-Disease Clinical Leadership

Trimaren Human Capital Partners; Watertown (TN); On-site; USD 409,000 - 554,000; Full time

Job summary

Confidential Biotech seeks a Chief Medical Officer to lead clinical development for its precision medicine portfolio in severe hematologic diseases. You will shape medical governance, set strategy, and represent the company with credibility to regulators, investors, and the scientific community.

Ideal candidate has 15+ years in clinical and biopharma/biotech, with at least 5 years in VP-level leadership, extensive IND experience, and a record of cross-functional leadership across R&D,

Qualifications

• MD required; residency and fellowship training in hematology or closely related discipline.
• Board certification in hematology strongly preferred; pediatric hematology, hematology/oncology, or internal medicine with deep hematology focus will also be considered.

Responsibilities

• Own the overall clinical development strategy for the company's precision medicine portfolio in severe hematologic disease, aligning medical plans with program goals, regulatory expectations, and long-term value creation.
• Lead translational strategy, clinical pharmacology planning, dose optimization, biomarker strategy, endpoint selection, and evidence generation to support go/no-go decisions and milestones.
• Serve as the primary medical lead for interactions with health authorities, including IND submissions, early regulatory meetings, and rare-disease discussions.
• Oversee safety governance, medical monitoring, pharmacovigilance, and benefit-risk assessment to ensure patient protection and high-quality clinical execution.
• Partner with Research, Nonclinical, CMC, Clinical Operations, Regulatory Affairs, and future Commercial colleagues to ensure development plans are rigorous and executable.
• Build external medical presence through investigator engagement, KOL relationships, publication planning, medical education, advisory boards, and communications with Board and investors.

Education

MD

Residency & Fellowship in Hematology

Job description

Confidential Biotech seeks a Chief Medical Officer to lead clinical development for its precision medicine portfolio in severe hematologic diseases. You will shape medical governance, set strategy, and represent the company with credibility to regulators, investors, and the scientific community.

Ideal candidate has 15+ years in clinical and biopharma/biotech, with at least 5 years in VP-level leadership, extensive IND experience, and a record of cross-functional leadership across R&D,