Remote Biology Scientist - Target Validation & UniProt

YO AI Labs; Seattle (WA); Remote; USD 83,000 - 165,000; Part time

Job summary

YO AI Labs is seeking an experienced Biology Research Scientist to validate protein target assignments against primary literature and UniProt records. You will review papers, compare with UniProt, and identify discrepancies, proposing corrected UniProt accessions with concise reasoning.

The role requires bench-based expertise in pharmacology, biochemistry, and molecular biology, with experience in common binding assays and data interpretation. Remote, contractor collaboration, immediate start.

Qualifications

• BA/BS + 5 years, MS + 2 years, or PhD with relevant industry/drug discovery experience.
• Background in pharmacology, biochemistry, molecular biology, or chemical biology within biotech, pharma, or CRO environments.
• Hands-on experience with assays such as SPR, TR-FRET, radioligand binding, kinase assays, or GPCR functional assays.
• Experience interpreting IC50, Ki, and Kd data.
• Currently active in bench-based research, scientist, or associate scientist role.
• Working knowledge of UniProt or related workflows such as SAR, HTS, target validation, biochemical profiling, or IND-enabling studies.

Responsibilities

• Review primary research papers and patents to verify protein target assignments.
• Compare target assignments against UniProt and identify discrepancies.
• Classify target assignment errors using a structured taxonomy.
• Propose accurate UniProt accessions where assignments are incorrect.
• Document clear, evidence-grounded reasoning for each determination.
• Apply pharmacology, biochemistry, molecular biology, or chemical biology expertise to evaluate target relationships.

Skills

Protein Target Identification

UniProt

Primary Literature Review

Protein Biochemistry

Molecular Biology

Pharmacology

Binding & Functional Assays

Scientific Data Interpretation

Evidence-Based Reasoning

Technical Documentation

Education

BA/BS + 5 years

MS + 2 years

PhD with relevant industry experience

Tools

SPR

TR-FRET

Radioligand Binding

Kinase Assays

GPCR Functional Assays

Job description

YO AI Labs is seeking an experienced Biology Research Scientist to validate protein target assignments against primary literature and UniProt records. You will review papers, compare with UniProt, and identify discrepancies, proposing corrected UniProt accessions with concise reasoning.

The role requires bench-based expertise in pharmacology, biochemistry, and molecular biology, with experience in common binding assays and data interpretation. Remote, contractor collaboration, immediate start.