Biology Research Scientist - Target Validation & UniProt

YO AI Labs; Boston (MA); Remote; USD 55.000 - 96.000; Teilzeit

Zusammenfassung

YO AI Labs is seeking a Biology Research Scientist on a remote, contractor basis to validate protein target assignments against primary literature and UniProt records. You will review papers and patents, identify errors, and propose corrected UniProt accessions with concise, evidence-based reasoning.

The role requires bench experience in pharmacology, biochemistry, molecular biology, or chemical biology and familiarity with UniProt workflows.

Qualifikationen

• BA/BS + 5 years, MS + 2 years, or PhD with relevant industry/drug discovery experience.
• Background in pharmacology, biochemistry, molecular biology, or chemical biology within biotech, pharma, or CRO environments.
• Hands-on experience with assays such as SPR, TR-FRET, radioligand binding, kinase assays, or GPCR functional assays.
• Experience interpreting IC50, Ki, and Kd data.
• Currently active in bench-based research, scientist, or associate scientist role.
• Working knowledge of UniProt or related workflows such as SAR, HTS, target validation, biochemical profiling, or IND-enabling studies.

Aufgaben

• Review primary research papers and patents to verify protein target assignments.
• Compare target assignments against UniProt and identify discrepancies.
• Classify target assignment errors using a structured taxonomy.
• Propose accurate UniProt accessions where assignments are incorrect.
• Document clear, concise, evidence-grounded reasoning for each determination.
• Apply expertise in pharmacology, biochemistry, molecular biology, or chemical biology to evaluate target relationships.

Kenntnisse

Protein Target ID

UniProt

Primary Lit Review

Protein Biochemistry

Molecular Biology

Pharmacology

Binding Assays

Data Interpretation

Evidence Reasoning

Technical Documentation

Ausbildung

BA/BS + 5 years

MS + 2 years

PhD with industry experience

Tools

UniProt

SAR

HTS

Jobbeschreibung

YO AI Labs is seeking a Biology Research Scientist on a remote, contractor basis to validate protein target assignments against primary literature and UniProt records. You will review papers and patents, identify errors, and propose corrected UniProt accessions with concise, evidence-based reasoning.

The role requires bench experience in pharmacology, biochemistry, molecular biology, or chemical biology and familiarity with UniProt workflows.