Remote Biology Research Scientist: Target Validation

YO AI Labs; Los Angeles (CA); À distance; USD 83 000 - 138 000; Plein temps

Résumé du poste

YO AI Labs is seeking experienced Biology Research Scientists to support a remote project validating protein target assignments against primary sources and UniProt records. You will review papers, identify errors, and propose corrected UniProt accessions with concise, evidence-based explanations.

Requirements include a BA/BS with 5+ years, MS with 2+ years, or PhD in pharmacology/biochemistry/molecular biology/chemical biology and hands-on experience with relevant assays.

Qualifications

• BA/BS + 5 years, MS + 2 years, or PhD with relevant industry/drug discovery experience.
• Background in pharmacology, biochemistry, molecular biology, or chemical biology within biotech, pharma, or CRO environments.
• Hands-on experience with assays such as SPR, TR-FRET, radioligand binding, kinase assays, or GPCR functional assays.
• Experience interpreting IC50, Ki, and Kd data.
• Currently active in a bench-based research, scientist, or associate scientist role.
• Working knowledge of UniProt or related workflows such as SAR, HTS, target validation, biochemical profiling, or IND-enabling studies.

Responsabilités

• Review primary research papers and patents to verify protein target assignments.
• Compare target assignments against UniProt and identify discrepancies.
• Classify target assignment errors using a structured taxonomy.
• Propose accurate UniProt accessions where assignments are incorrect.
• Document clear, concise, evidence-grounded reasoning for each determination.
• Apply expertise in pharmacology, biochemistry, molecular biology, or chemical biology to evaluate target relationships.

Connaissances

Protein Target Identification

UniProt

Primary Literature Review

Protein Biochemistry

Molecular Biology

Pharmacology

Binding & Functional Assays

Scientific Data Interpretation

Evidence-Based Reasoning

Technical Documentation

Formation

BA/BS + 5 years / MS + 2 years / PhD with relevant industry experience

Outils

SPR

TR-FRET

Radioligand Binding

Kinase Assays

GPCR Functional Assays

UniProt Workflows

SAR

HTS

IND-enabling Studies

Description du poste

YO AI Labs is seeking experienced Biology Research Scientists to support a remote project validating protein target assignments against primary sources and UniProt records. You will review papers, identify errors, and propose corrected UniProt accessions with concise, evidence-based explanations.

Requirements include a BA/BS with 5+ years, MS with 2+ years, or PhD in pharmacology/biochemistry/molecular biology/chemical biology and hands-on experience with relevant assays.