Remote AI Biologist — Peptide Discovery Scientist

LatchBio; United States; Remoto; USD 120.000 - 180.000; Tempo pieno

Vantaggi offerti da questo lavoro

Onsite perks: catered lunch and dinner

Waterfront office in Mission Bay (SF)

Descrizione del lavoro

LatchBio seeks an AI Biologist to join the Peptide Discovery team, pushing what AI can achieve in therapeutic peptide discovery. You will be the scientific authority on ground truth, testing whether agents can reason like an expert peptide discovery scientist and make calls that move a peptide from target to candidate.

You will collaborate with software engineers and scientists to build tasks and datasets across linear, macrocyclic, and constrained peptides against protein targets, including

Competenze

• PhD in peptide chemistry or related field.
• Senior, hands-on peptide discovery experience with real program data.
• Experience with at least one of: display/selection, binding kinetics, mapping, or developability.
• Strong data analysis in Python or R; experimental design.
• AI-ready and able to judge model outputs.

Mansioni

• Define expert reasoning standards and write gold-standard answers with the rationale an experienced peptide scientist would defend
• Design realistic scenarios across discovery arc: target tractability, hit generation, hit confirmation and kinetics, binding-site mapping, functional confirmation, and lead optimization
• Curate datasets from real programs: display-selection read counts, SPR/BLI sensorgrams, fluorescence-polarization titrations, affinity-selection MS, HDX-MS, crosslinking-MS, NMR chemical-shift perturbation, dose-response, and permeability and stability data
• Build analysis pipelines in Python, from enrichment analysis to kinetic and dose-response fitting, that produce verifiable ground truth with tolerances that hold across replicates and fitting routines
• Partner with software engineers to turn your judgment into new workflows

Conoscenze

Python

R

Data analysis

Experimental design

AI readiness

Formazione

PhD in peptide chemistry/related field

Strumenti

SPR/BLI

NMR

HDX-MS

Mass spectrometry

Descrizione del lavoro

LatchBio seeks an AI Biologist to join the Peptide Discovery team, pushing what AI can achieve in therapeutic peptide discovery. You will be the scientific authority on ground truth, testing whether agents can reason like an expert peptide discovery scientist and make calls that move a peptide from target to candidate.

You will collaborate with software engineers and scientists to build tasks and datasets across linear, macrocyclic, and constrained peptides against protein targets, including