AI Proteomics Biologist — Mass Spec Expert (Remote/Hybrid)

Latch Bio, Inc.; San Francisco (CA); Hybrid; USD 140,000 - 180,000; Full time

Job summary

Latch Bio, Inc. is seeking an AI Biologist to lead the Proteomics team and define ground-truth reasoning for mass spectrometry workflows.

You will shape tasks, datasets, and evaluation criteria across proteomics, lipidomics, and metabolomics, collaborating with software engineers to embed expert judgment into new AI-enabled workflows. You will set standards for detecting true biological signals, distinguishing artifacts, and guiding how AI agents should reason and respond.

Qualifications

• PhD in proteomics or related field required.
• Hands-on mass spectrometry experience with data analysis.
• Mass spec experience beyond proteomics: lipidomics/metabolomics preferred.
• Strong experimental design and statistics knowledge.
• AI-ready from day one: familiar with Claude/Cursor or similar.
• Willingness to overrule AI when evidence demands it.
• Bonus: protein sequencing or antibody experience.

Responsibilities

• Define expert reasoning for MS questions and write gold-standard answers with justified rationale.
• Design real-world scenarios across sample prep, acquisition, identification, quantification, and interpretation.
• Curate MS datasets across proteomics and omics fields; include antibody/sequencing data when relevant.
• Collaborate with software engineers to implement new workflows based on judgment.
• Test whether agents distinguish true biological signal from artifacts or batch effects.
• Adjudicate ambiguous results and decide data-supported conclusions.

Skills

AI judgement

Experiment design

Statistical analysis

Mass spectrometry experience

Publication track record

Education

PhD in proteomics

Tools

Mass spectrometry software

Job description

Latch Bio, Inc. is seeking an AI Biologist to lead the Proteomics team and define ground-truth reasoning for mass spectrometry workflows.

You will shape tasks, datasets, and evaluation criteria across proteomics, lipidomics, and metabolomics, collaborating with software engineers to embed expert judgment into new AI-enabled workflows. You will set standards for detecting true biological signals, distinguishing artifacts, and guiding how AI agents should reason and respond.