QC Scientist I, 2nd Shift — RNAi Therapeutics

Arrowhead Pharmaceuticals; Madison (WI); On-site; USD 85,000 - 120,000; Full time

Benefits offered by this job

Excellent benefit package

Job summary

Arrowhead Pharmaceuticals, a commercial-stage biopharmaceutical company, seeks a Scientist I, Quality Control to join the Verona, WI team. You will support analytical method validation, method transfer, and QC testing across our RNAi therapeutic pipeline in a fast-paced GMP laboratory.

You’ll serve as a technical resource, solve analytical problems, and help ensure product quality and compliance. The role emphasizes collaboration with Analytical Development and Manufacturing, leading

Qualifications

• Bachelor's or Master's in Chemistry with 3+–5+ years of lab experience.
• Knowledge of cGMP and ICH laboratory requirements and operations.
• Experience testing oligonucleotides, peptides, or other synthetic biomolecules.

Responsibilities

• Perform analytical testing of materials and products using validated methods.
• Execute method validation, transfer, and routine QC testing per cGMP/ICH.
• Operate and troubleshoot LC-MS, HPLC/UHPLC, GC, and other instrumentation.
• Interpret data and support stability studies and degradation profiles.
• Collaborate cross-functionally to support product development and manufacturing.
• Train colleagues on analytical techniques and ensure proper documentation.
• Maintain compliant lab records and support investigations.

Skills

Attention to detail

Documentation accuracy

Analytical problem solving

Education

Bachelor's degree in Chemistry or related

Master's degree in Chemistry or related

Tools

LC-MS

AEX-HPLC

RP-HPLC/UHPLC

Karl Fischer

LAL testing

Job description

Arrowhead Pharmaceuticals, a commercial-stage biopharmaceutical company, seeks a Scientist I, Quality Control to join the Verona, WI team. You will support analytical method validation, method transfer, and QC testing across our RNAi therapeutic pipeline in a fast-paced GMP laboratory.

You’ll serve as a technical resource, solve analytical problems, and help ensure product quality and compliance. The role emphasizes collaboration with Analytical Development and Manufacturing, leading