Principal Scientist, Small Molecule Process Development

TalentAlly; Cambridge (MA); On-site; USD 159,000 - 219,000; Full time

Benefits offered by this job

Competitive base salary

Bonus opportunities

Equity incentive

Benefits package

Paid time off

Job summary

Biogen seeks a Principal Scientist, Chemistry in Cambridge, MA to lead development of robust manufacturing processes for small molecules and mentor scientific teams across modalities. The role spans from early phase to late phase drug development and includes exposure to process design and tech transfer for clinical and commercial therapeutics.

You will guide collaborative projects, interact with CROs/CMOs, publish CMC sections for INDs, and represent Biogen in external consortia and

Qualifications

• Ph.D. with 8+ years of relevant experience in pharmaceutical or biotech settings.
• MS with 10+ years of relevant experience in pharmaceutical or biotech settings.
• BS with 12+ years of relevant experience in pharmaceutical or biotech settings.
• Strong background in pharmaceutical chemistry, route scouting, mechanistic experiments, and process safety.

Responsibilities

• Lead collaborative development for manufacturing teams to design and conduct laboratory experiments to optimize and characterize processes.
• Design and lead experimental planning to advance Biogen portfolio and implement safe, efficient chemical processes.
• Mentor less experienced staff and promote use of key laboratory instrumentation.
• Develop fundamental process knowledge to support transition from lab to manufacturing partners.
• Collaborate with Process Chemistry, Analytical Chemistry, and other teams to support regulatory filings.

Skills

Leadership

Analytical chemistry

Problem solving

Process understanding

Regulatory knowledge

Education

Ph.D. in Chemistry

M.S. in Chemistry

Tools

CDMO management

Process characterization tools

Analytical instrumentation

Job description

Biogen seeks a Principal Scientist, Chemistry in Cambridge, MA to lead development of robust manufacturing processes for small molecules and mentor scientific teams across modalities. The role spans from early phase to late phase drug development and includes exposure to process design and tech transfer for clinical and commercial therapeutics.

You will guide collaborative projects, interact with CROs/CMOs, publish CMC sections for INDs, and represent Biogen in external consortia and