Preclinical Pharmacology Scientist - Neuro & Immunology

EMD Serono, Inc.; Billerica (MA); On-site; USD 90,000 - 136,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Retirement contributions

Other perquisites

Job summary

EMD Serono, Inc. is seeking a Scientist II, Preclinical Pharmacology in Massachusetts to lead in vivo pharmacology studies across immunology, neuroscience, and fertility areas.

You will execute disease-model studies with diverse routes and contribute to translational PK/PD strategies and biomarker readouts. Join a multidisciplinary team advancing innovative therapies; the role emphasizes independent scientific execution, data packaging, and collaboration with internal and external partners while

Qualifications

• PhD in Pharmacology, Neuroscience, Immunology, Physiology, or other life science discipline with 4+ years of drug discovery experience in a pharmaceutical or biotech industry setting.
• Master’s degree in Pharmacology, Neuroscience, Immunology, Physiology, or other life science discipline with 6+ years of drug discovery experience in a pharmaceutical or biotech industry setting.
• Bachelor’s degree in Pharmacology, Neuroscience, Immunology, Physiology, or other life science discipline with 8+ years of drug discovery experience in a pharmaceutical or biotech industry setting.

Responsibilities

• Establish, validate, optimize, and troubleshoot fit-for-purpose in vivo disease models — including acute and chronic disease-relevant models — to defined validation milestones and reproducibility criteria
• Build and apply immunological and/or neurological disease models to evaluate efficacy, target engagement, pharmacodynamic response, and translational relevance of novel therapeutic approaches, delivering study-ready data packages on schedule and in compliance with protocol and quality standards
• Hands on execution of in vivo pharmacology studies in disease models — including dosing via IV, SC, IP, PO, ICV, and IT routes, blood and CSF sampling, tissue collection, and necropsy — delivering study-ready samples on schedule and in compliance with protocol and quality standards
• Perform and support surgical procedures relevant to broad set of pharmacology assays, including but not limited to surgical models, ICV/IT administration, stereotaxic injections, surgical recovery monitoring, and clinical scoring, to define procedural and welfare standards
• Support in vivo pharmacology studies by conducting broad, standardized assessments of functional, behavioral, and physiological endpoints across preclinical disease models, enabling robust evaluation of treatment-related effects
• Support biomarker strategy execution, including fluid, tissue, molecular, inflammatory, and translatable biomarker readouts
• Manage CRO partnerships and external study execution, extending the laboratory’s capacity and geographic reach, ensuring program timelines are maintained without compromising scientific standards
• Champion IACUC & AAALAC compliance across the in vivo function

Skills

In vivo pharmacology

PK/PD expertise

Biomarker assays

Education

PhD in Pharmacology/ Neuroscience/ Immunology/ Physiology

Master’s in Pharmacology/ Neuroscience/ Immunology/ Physiology

Bachelor’s in Pharmacology/ Neuroscience/ Immunology/ Physiology

Job description

EMD Serono, Inc. is seeking a Scientist II, Preclinical Pharmacology in Massachusetts to lead in vivo pharmacology studies across immunology, neuroscience, and fertility areas.

You will execute disease-model studies with diverse routes and contribute to translational PK/PD strategies and biomarker readouts. Join a multidisciplinary team advancing innovative therapies; the role emphasizes independent scientific execution, data packaging, and collaboration with internal and external partners while