Preclinical CAR T Immunology Scientist (On-Site) - Stock Options

Cabaletta Bio Inc.; Philadelphia (Philadelphia County); On-site; USD 95,000 - 130,000; Full time

Benefits offered by this job

Stock options

Competitive benefits

PTO

Job summary

Cabaletta Bio Inc. in Philadelphia, PA, is seeking a highly skilled Scientist with expertise in cell-based assays for CAR T cell therapy to join our Cellular Immunology Preclinical team.

You will develop in vitro, ex vivo, and in vivo assays to advance safety and efficacy of CAR T cells, collaborate with multidisciplinary colleagues, and contribute to the RESET program in autoimmune diseases. Experience with flow cytometry and cytotoxicity assays is valued.

Qualifications

• PhD in Immunology, Cell Biology, Molecular Biology or related field with 0–2 years, or Master’s with at least 5 years, or Bachelor’s with at least 10 years experience.
• Hands-on experience with cell culture and basic molecular biology techniques.
• Aseptic techniques and human tissue handling experience required.
• Mammalian cell culture (aseptic) expertise essential.
• Experience in cytotoxicity assays and flow cytometry preferred.

Responsibilities

• Perform hands-on lab experiments to maintain, bank, and manage cell lines and generate CAR T cells.
• Conduct cytotoxicity and flow cytometry assays and validate results.
• Execute ELISpot, ELISA, Luminex or MSD assays as needed.
• Follow Cabaletta lab safety policies and SOPs in all tasks.
• Oversee in vivo mouse studies and related ex vivo assays.
• Maintain clean and organized lab equipment and spaces.
• Keep accurate records and electronic lab notebooks.
• Analyze data using basic statistics and software tools.
• Collaborate within a multidisciplinary team and participate in meetings.
• Communicate findings via written reports and oral presentations.

Skills

Immunology research

Team collaboration

Scientific writing

Data interpretation

Education

Ph.D. in Immunology or related field

M.S. in Immunology or related field

B.S. in related field

Tools

Mammalian cell culture

Flow cytometry

ELISA/ELISpot/Luminex/MSD assays

In vivo mouse handling

Data analysis software

Job description

Cabaletta Bio Inc. in Philadelphia, PA, is seeking a highly skilled Scientist with expertise in cell-based assays for CAR T cell therapy to join our Cellular Immunology Preclinical team.

You will develop in vitro, ex vivo, and in vivo assays to advance safety and efficacy of CAR T cells, collaborate with multidisciplinary colleagues, and contribute to the RESET program in autoimmune diseases. Experience with flow cytometry and cytotoxicity assays is valued.